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OfflineDogomush
Barbless Aryan

Registered: 10/06/02
Posts: 1,286
Loc: The Canadian west coast
Last seen: 17 years, 8 months
Mushrooms make your brain bleed, and that's the high!
    #1188822 - 01/04/03 04:26 AM (19 years, 10 months ago)

Yes, that's right. Somebody I know who has very strange ideas about drugs believes that mushrooms actually cause your brain to bleed and then you get high from that. I think the most fucked up thing about him is that even though this is what he truly believes, he still eats them on the rare occassion. Imagine eating something you "know" would make your brain bleed???

Maybe some of you can help me set him straight. His theory made me realize that I don't sound super smart when talking about how psilocybin acts in the brain. Here's how I would explain it to him currently:

"Psilocybin is structurally very similar to serotonin and DMT which are both natural neurotransmitters. It simply shunts serotonin to the side and makes use of its receptors until the body's monoamine oxidase enzymes break the psilocin down as it courses through the blood."

So some questions I have are: Where does the 9 day tolerance come from? Why does it happen? Increase in MAO? I understand that MAO breaks it down in the circulatory system. Does this mean that a psilocin molecule acts in the brain, then leaves into the blood and is either broken down or if not then makes it back to the receptor to go at it again? Or is each individual molecule used once and then recycled, pissed out or whatever? What would be the consequences of a brain bleeding from mushrooms, a stroke?

any additional info would be cool too. Help me crush a fool's soul people!!


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InvisibleXlea321
Stranger
Registered: 02/26/01
Posts: 9,134
Re: Mushrooms make your brain bleed, and that's the high! [Re: Dogomush]
    #1188922 - 01/04/03 05:40 AM (19 years, 10 months ago)

Good explanation but even the experts really have no idea. Melotonin is very similar to serotonin too and that isn't psychedelic. No-one really knows why mushrooms work.


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Don't worry, B. Caapi


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Anonymous

Re: Mushrooms make your brain bleed, and that's the high! [Re: Dogomush] * 2
    #1188981 - 01/04/03 06:51 AM (19 years, 10 months ago)

Don't forget to tell him that if it made your brain bleed then you'd be having a stroke and you'd die. Then tell hiim that he's a big fucking idiot. I don't know what I'd do if I knew someone that stupid. It would really make me mad.


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InvisibleBilge
longtimenoC

Registered: 08/26/02
Posts: 1,858
Loc: USA
Re: Mushrooms make your brain bleed, and that's the high! [Re: ]
    #1189277 - 01/04/03 12:03 PM (19 years, 10 months ago)

then see if you can sell them some banana peels. they're a real trip doncha know.


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Offlinedarkfly
LysergicExperimenter

Registered: 09/17/01
Posts: 1,169
Last seen: 7 years, 3 months
Re: Mushrooms make your brain bleed, and that's the high! [Re: Bilge]
    #1189332 - 01/04/03 12:44 PM (19 years, 10 months ago)

I heard bannana peels make your brain bleed, and that is why you trip.


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Everything Is Blue In This World. The Deepest Shade Of Mushroom Blue.


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OfflineAdamist
ℚṲℰϟ✞ЇѺℵ ℛ∃Åʟḯ†У
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Registered: 11/24/01
Posts: 10,211
Loc: Bloomington, IN
Last seen: 7 years, 8 months
Re: Mushrooms make your brain bleed, and that's the high! [Re: Dogomush]
    #1189506 - 01/04/03 02:42 PM (19 years, 10 months ago)

Quote:

Somebody I know who has very strange ideas about drugs believes that mushrooms actually cause your brain to bleed and then you get high from that.



Hahaha... Someone I know believes that, too.  :grin: 


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Offlinecelestialtripper
Test Pilot
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Registered: 08/02/02
Posts: 272
Last seen: 7 years, 2 months
Re: Mushrooms make your brain bleed, and that's the high! [Re: Adamist]
    #1189575 - 01/04/03 03:39 PM (19 years, 10 months ago)

some people around here think shrooms makes your stomach bleed and then the blood from your stomach bleeding is sent to your brain and thats how it makes you trip.


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OfflineAdamist
ℚṲℰϟ✞ЇѺℵ ℛ∃Åʟḯ†У
Male User Gallery

Registered: 11/24/01
Posts: 10,211
Loc: Bloomington, IN
Last seen: 7 years, 8 months
Re: Mushrooms make your brain bleed, and that's the high! [Re: celestialtripper] * 1
    #1189927 - 01/04/03 06:27 PM (19 years, 10 months ago)

Once I asked a local thug-dealer in my area if he knew where to get acid. He said "naw, dawg, dat shit is made outta rat poison. Da only reason u trips cuz it's poison, and yer actually diein thats why you see shit."
:tongue: 


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Invisiblefjbk47985
Has Been AbsentFor Far Too Long
Registered: 04/06/02
Posts: 758
Re: Mushrooms make your brain bleed, and that's the high! [Re: Adamist]
    #1190433 - 01/04/03 10:50 PM (19 years, 10 months ago)

lol...i hate that man...if u can convince some ppl that's awsome but don't bother arguing with one of those idiots whos super-convinced he's right..idiots like that just drag u down to their level and beat u with experience


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OfflinePsilocybeingzz
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Registered: 12/15/02
Posts: 14,463
Loc: International waters
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Re: Mushrooms make your brain bleed, and that's the high! [Re: fjbk47985]
    #1190820 - 01/05/03 02:30 AM (19 years, 10 months ago)

Psilocybin is like serotonin does serotonin make your brain bleed ??? no

In fact Psilocybin like LSD dampens the activity of the Raphe cells at the back of the brain
these cells are "inhibitors" and they inhibit some of the oldest most important parts of the brain and when LSD\Psilocybin comes in (this is the trippy part) LSD or Psilocybin dampens the Raphe cells
Inhibiting the Inhibitors

or put simply to this moron you know " Psilocybin lets the oldest parts of your brain go out and .....play... by telling the Raphe cells to cool their interference

science kicks ass
stupid people suck
long live Psilocybin!


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OfflineShamanSean
the MilitantMind

Registered: 11/21/02
Posts: 435
Loc: CA, USA, the Bay Area
Last seen: 18 years, 11 months
Re: Mushrooms make your brain bleed, and that's the high! [Re: fjbk47985]
    #1191012 - 01/05/03 04:08 AM (19 years, 10 months ago)

Its hard not to argue with ignorant people. For me, I just think about how much misinformation is out there already and I dont want it to spread. then I think that this dumb ass that im talkin to might not have a psychedellic experience his whole life cuz he was told lies by some other gullable ignorant fuck who was told by another one and so on and so on. A lotta times i feel like maybe if i set this person straight then itll b like a chain reaction eventually and they all will b set straight and may even try it.


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"So take my advice and dont quit. Cuz if u do, you wont get shit - bitch! "

-Too Short


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OfflineNeurotech
Stranger
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Registered: 05/05/20
Posts: 472
Last seen: 3 days, 4 hours
Re: Mushrooms make your brain bleed, and that's the high! [Re: Xlea321]
    #27174872 - 01/29/21 01:09 AM (1 year, 9 months ago)

Actually, Psilocybin is not psychoactive. It is not the psilocybin taking up residence in the serotonin receptors. Rather, psilocybin is broken down in the digestion process into psilocin, and that travels through the bloodstream to hook up with serotonin receptors.Psilocin, ultimately, is what is psychoactive.


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OfflineRise against
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Registered: 09/07/16
Posts: 255
Last seen: 1 year, 6 months
Re: Mushrooms make your brain bleed, and that's the high! [Re: Xlea321]
    #27174968 - 01/29/21 02:20 AM (1 year, 9 months ago)

Quote:

Xlea321 said:
Good explanation but even the experts really have no idea. Melotonin is very similar to serotonin too and that isn't psychedelic. No-one really knows why mushrooms work. 




What's crazy is that melatonin is so similar to psilocybin that it could be considered a schedule 1 drug because of the analog act.


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OfflineskOsH
a little bit of chaos
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Registered: 07/04/19
Posts: 1,054
Loc: the PNW
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Re: Mushrooms make your brain bleed, and that's the high! [Re: Rise against]
    #27177929 - 01/30/21 09:34 PM (1 year, 9 months ago)

Quote:

Rise against said:
Quote:

Xlea321 said:
Good explanation but even the experts really have no idea. Melotonin is very similar to serotonin too and that isn't psychedelic. No-one really knows why mushrooms work. 




What's crazy is that melatonin is so similar to psilocybin that it could be considered a schedule 1 drug because of the analog act.




Agreed, it's basically an indole which can easily be made into psychoactives


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LSD should be legalized for adult consumption


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OfflineDr. Delban
Incognito hippie in disguise
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Registered: 09/29/12
Posts: 1,990
Loc: UK Flag
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Re: Mushrooms make your brain bleed, and that's the high! [Re: Dogomush]
    #27178181 - 01/31/21 01:06 AM (1 year, 9 months ago)

Quote:

Dogomush said:
Yes, that's right. Somebody I know who has very strange ideas about drugs believes that mushrooms actually cause your brain to bleed and then you get high from that. I think the most fucked up thing about him is that even though this is what he truly believes, he still eats them on the rare occassion.




His brain doesn't bleed because he doesn't have one, so he can eat mushies as much as he wants.

NEXT PLEASE!


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Experimenting with sobriety


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OfflineDr. Delban
Incognito hippie in disguise
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Registered: 09/29/12
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Re: Mushrooms make your brain bleed, and that's the high! [Re: celestialtripper]
    #27178183 - 01/31/21 01:08 AM (1 year, 9 months ago)

Quote:

celestialtripper said:
some people around here think shrooms makes your stomach bleed and then the blood from your stomach bleeding is sent to your brain and thats how it makes you trip.




Do they eat broken glass if they can't obtain any gear?


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Experimenting with sobriety


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Offlinejgotti
Stranger
Registered: 09/03/11
Posts: 112
Last seen: 1 day, 8 hours
Re: Mushrooms make your brain bleed, and that's the high! [Re: Dogomush]
    #27178211 - 01/31/21 01:33 AM (1 year, 9 months ago)

Actually the opposite is true, in terms of bleeding. 5-HT2A agonists help regulate platelet function. Platelets express 5-HT2A receptors, and activation of these receptors helps promote blood coagulation.

Psilocybin/psilocin is a potent 5-HT2A agonist.


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Invisibleevlyshrooms
willi weilii
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Registered: 08/08/19
Posts: 1,861
Re: Mushrooms make your brain bleed, and that's the high! [Re: jgotti]
    #27178220 - 01/31/21 01:39 AM (1 year, 9 months ago)

you guys realize this thread is from 2003?


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OfflineDr. Delban
Incognito hippie in disguise
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Registered: 09/29/12
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Re: Mushrooms make your brain bleed, and that's the high! [Re: evlyshrooms]
    #27179322 - 01/31/21 09:03 PM (1 year, 9 months ago)

Quote:

evlyshrooms said:
you guys realize this thread is from 2003?




No.


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Experimenting with sobriety


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OfflineNeurotech
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Registered: 05/05/20
Posts: 472
Last seen: 3 days, 4 hours
Re: Mushrooms make your brain bleed, and that's the high! [Re: skOsH]
    #27188210 - 02/06/21 12:28 AM (1 year, 9 months ago)

Quote:

skOsH said:
Quote:

Rise against said:
Quote:

Xlea321 said:


Agreed, it's basically an indole which can easily be made into psychoactives




Do you have some info on this I could refer to?


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