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OfflineDr. Slavic
enthusiast
Registered: 10/06/02
Posts: 252
Last seen: 14 years, 6 days
4 HO-dmt
    #1161796 - 12/22/02 08:59 AM (15 years, 4 months ago)

From Tihkal
"Some fascinating studies have been done in Germany where the metabolically active mycelium of some Psilocybe species have been administered diethyltryptamine as a potential diet component. Normally, this mushroom species dutifully converts N,N-dimethyltryptamine (DMT) to psilocin, by introducing a 4-hydroxyl group into the molecule by something that is probably called an indole 4-hydroxylase by the biochemists. You put DMT in, and you get 4-hydroxy-DMT out, and this is psilocin. Maybe if you put Mickey Mouse in, you would get 4-hydroxy-Mickey Mouse out. It is as if the mushroom psyche didn't really care what it was working with, it was simply compelled to do its sacred duty to 4-hydroxylate any tryptamine it came across. It was observed that if you put N,N-diethyltryptamine (DET, not a material found in nature) into the growing process, the dutiful and ignorant enzymes would hydroxylate it to 4-hydroxy-N,N-diethyltryptamine (4-HO-DET) a potent drug also not known in nature."

Does anyone have info on this. Like what psilocybe species will add the 4 hydroxyl group on tryptamines and how much tryptamine can be converted. This is very interesting since dmt can be made from tryptophol, dimethylamine and Ni in a non-polar solvent in high yeild.


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OfflineDr. Slavic
enthusiast
Registered: 10/06/02
Posts: 252
Last seen: 14 years, 6 days
Re: 4 HO-dmt [Re: Dr. Slavic]
    #1168451 - 12/24/02 08:09 PM (15 years, 4 months ago)

Anyone?? Any info at all??


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Offlinepsychopsilocyber
[_381_] gnemo

Registered: 12/11/02
Posts: 1,020
Loc: glyphtown
Last seen: 5 years, 5 months
Re: 4 HO-dmt [Re: Dr. Slavic]
    #1168468 - 12/24/02 08:18 PM (15 years, 4 months ago)

There was a post about this before, do a search. Im pretty sure cubensis does this.


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Invisiblematts
matts

Registered: 01/28/02
Posts: 3,649
[Re: Dr. Slavic]
    #1168685 - 12/24/02 11:30 PM (15 years, 4 months ago)



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Mushrooms, Mycology and Psychedelics >> The Psychedelic Experience

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