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OfflineGanja-Guru

Registered: 10/04/09
Posts: 187
Last seen: 3 years, 6 months
Eating Weilii then eating Amanita?
    #11293006 - 10/21/09 05:41 PM (8 years, 9 hours ago)

After eating Weilii today a friend ALSO injested some Amanita Muscaria ontop of it all...Now Im no chemist and don't expect anyone else here to be one...but I gotta ask..."Seeing as how they contain TWO TOTALLY DIFFERENT CHEMICALS, is this safe?" Is there a bad interaction here?


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Offlinekydelic
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Registered: 06/08/09
Posts: 371
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Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11293156 - 10/21/09 06:01 PM (8 years, 9 hours ago)

No, mostly because they're TWO TOTALLY DIFFERENT CHEMICALS as you say (sorry, being cheeky :wink: ). They act on different types of receptors and, as far as I know, do not interact. Neither is an MAOI either.


--------------------
http://flickr.com/photos/mycography - A collection of my fungal photography


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OfflineGanja-Guru

Registered: 10/04/09
Posts: 187
Last seen: 3 years, 6 months
Re: Eating Weilii then eating Amanita? [Re: kydelic]
    #11293222 - 10/21/09 06:11 PM (8 years, 8 hours ago)

So when, or by what proccess do things start getting fucked up in your brain? I assume you have to take two drugs that act on the same recepter in opposite ways...huh? Is that when things get bad? I notice that Muscimol is a GABA agonist - are you saying that you have to take something else that would affect the same receptor?


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InvisibleShad0w
In trouble again.
Male

Registered: 06/08/08
Posts: 3,639
Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11293316 - 10/21/09 06:23 PM (8 years, 8 hours ago)

I cant answer any of those questions offhand....

But I can tell you why it ISNT safe for your friend to do....

... He doesnt know if they are a bad combo.

AND YET. He ate em anyway?



Well, have him report back.


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Invisiblethedudenj
Man of the Woods

Registered: 08/18/04
Posts: 14,684
Re: Eating Weilii then eating Amanita? [Re: Shad0w]
    #11293556 - 10/21/09 07:00 PM (8 years, 8 hours ago)

take amanita first and in the first hour eat the weilii


--------------------

"You all are just  puppets... You have no heart...and cannot feel any pain...""
you may think thats pain you feel but you must have a heart to feel true pain and that pain wont be yours


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OfflineLSDreamer
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Registered: 03/11/08
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Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11293583 - 10/21/09 07:04 PM (8 years, 8 hours ago)

Quote:

Ganja-Guru said:
So when, or by what proccess do things start getting fucked up in your brain? I assume you have to take two drugs that act on the same recepter in opposite ways...huh? Is that when things get bad? I notice that Muscimol is a GABA agonist - are you saying that you have to take something else that would affect the same receptor?




What, exactly, are you asking? Are you asking for general guidelines as to what drugs are likely to interact badly?


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Offlinekydelic
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Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11295135 - 10/21/09 10:28 PM (8 years, 4 hours ago)

Quote:

Ganja-Guru said:
So when, or by what proccess do things start getting fucked up in your brain? I assume you have to take two drugs that act on the same recepter in opposite ways...huh? Is that when things get bad? I notice that Muscimol is a GABA agonist - are you saying that you have to take something else that would affect the same receptor?




The process of how all this works is explained much better than I could put it right now in Wikipedia for the specific mushrooms. Basically, the chemicals in the fly agarics resemble the structure of the glutamate and GABA neurotransmitters, and so 'fit in' to certain receptors, in this case the muscarinic acetylcholine receptors. Agonists cause neurons to fire.

Psilocybin/psilocin work on your serotonin receptors, which are located in different parts of the brain and have totally different effects. Since these don't inhibit normal breakdown or really interact too much (as far as I can tell, I'd recommend reading experience reports and seeing what people say), they shouldn't have bad interactions. AFAIK the thing you have to worry about are MAOIs...what your friend did was dumb though.


--------------------
http://flickr.com/photos/mycography - A collection of my fungal photography


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OfflineGanja-Guru

Registered: 10/04/09
Posts: 187
Last seen: 3 years, 6 months
Re: Eating Weilii then eating Amanita? [Re: kydelic]
    #11295209 - 10/21/09 10:35 PM (8 years, 4 hours ago)

Yes, mixing any types of drugs without proper schooling is irresponsible and neglectful. He's fine though. Its just my "worry body" habit to ask questions that deal with the safety of friends and family.


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Offlinegurknel
GuRkNeL


Registered: 09/19/08
Posts: 701
Last seen: 1 year, 6 months
Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11295257 - 10/21/09 10:41 PM (8 years, 4 hours ago)

How did he like it?


--------------------
:cheech: :chong: :flyhigh: :lsd: :jah:


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InvisiblePolk_Audio3
"Swisher Sweets"
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Registered: 02/17/09
Posts: 6,888
Loc: Amsterdam
Re: Eating Weilii then eating Amanita? [Re: gurknel]
    #11295307 - 10/21/09 10:46 PM (8 years, 4 hours ago)

You might have one of those "lost" trips..:shrug: you will make it though


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OfflineGanja-Guru

Registered: 10/04/09
Posts: 187
Last seen: 3 years, 6 months
Re: Eating Weilii then eating Amanita? [Re: Polk_Audio3]
    #11297759 - 10/22/09 07:18 AM (7 years, 11 months ago)

He was good, he's a pretty consistant/wise "journey taker". He does say that the Weilii serve as being the most positive and welcoming trip he has ever had. Even upon attempting to toy with negative thought patterns, he found himself forgeting that he was doing so and going on to the next beautiful set of thoughts...lol


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OfflineManyAk
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Registered: 01/21/09
Posts: 1,081
Loc: Somewhere but not here
Last seen: 1 year, 9 months
Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11297768 - 10/22/09 07:28 AM (7 years, 11 months ago)

Well I'm glad things turned out for the best man. But in all seriousness, don't freaking eat mushrooms if you don't know their effects.


--------------------
                                  we are all luminous beings
why then do we not appear before each other radiant in our illumination

-----------------------------------------------------

ART.http://insidemanyak.blogspot.com/


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OfflineGanja-Guru

Registered: 10/04/09
Posts: 187
Last seen: 3 years, 6 months
Re: Eating Weilii then eating Amanita? [Re: ManyAk]
    #11301944 - 10/22/09 09:08 PM (7 years, 11 months ago)

In all seriousness...I didn't...no need to be coy about this...I asked about a friend because thats who ate them, not myself. Thanks for the concern.


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OfflineGanja-Guru

Registered: 10/04/09
Posts: 187
Last seen: 3 years, 6 months
Re: Eating Weilii then eating Amanita? [Re: Ganja-Guru]
    #11301953 - 10/22/09 09:10 PM (7 years, 11 months ago)

His name is Shane, ManyAk. Trust in me.


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