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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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mushroom cross tolerance
    #11028703 -

is there a cross tolerance between mushrooms and cacti? cuz i wanna trip tonight on mushrooms but i  dont want tolerance to interfere with my san pedro trip in 4 or so days.


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My old Papaver Somniferums var. Gigantum and my Passion Flower...

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Re: mushroom cross tolerance [Re: fatso]
    #11028762 -

no...different chemicals altogether


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Treasure Every Moment

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Re: mushroom cross tolerance [Re: rovert]
    #11028819 -

ok cuz i know there definetly is with lsd


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My old Papaver Somniferums var. Gigantum and my Passion Flower...

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Re: mushroom cross tolerance [Re: fatso]
    #11028832 -

yea none of the same active chemicals so there shouldnt be...unless its just i your head :ganja:


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Treasure Every Moment

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Re: mushroom cross tolerance [Re: rovert]
    #11028908 -

well psilocybin and lsd are different chems and still have cross tolerance so it could be.


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My old Papaver Somniferums var. Gigantum and my Passion Flower...

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Re: mushroom cross tolerance [Re: fatso]
    #11029513 -

well i read in a few other posts it seems like there is cross tolereance.

Corrrect?


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My old Papaver Somniferums var. Gigantum and my Passion Flower...

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Re: mushroom cross tolerance [Re: fatso]
    #11029655 -

"The most direct support for this inference of biological identity in ultimate mechanism of action has come from cross-tolerance studies wherein subjects rendered tolerant to one drug—that is, nonreactive after repeated administrations —have then been challenged by a different drug. Present indications are that cross-tolerance among the drugs does in fact develop (14)."


http://www.psychedelic-library.org/unger.htm

"Tolerance develops rapidly, repeated daily doses become completely ineffective in 3-4 days. Cross tolerance has been shown between LSD, mescaline and psilocybin and the effects of each can be blocked or reversed with chlorpromazine (antipsychotic). Most behavioral effects of LSD and the catechol hallucinogens can be blocked by drugs that act as serotonin-receptor antagonists "


http://www.u.arizona.edu/~tommyb/Hallucinogens.html

Probably using the same source for the information as the other link though.... Found a few others that are worded as if they came from the same source as well.

So..... IF what that source says is true. I dunno.  :shrug:

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Re: mushroom cross tolerance [Re: Shad0w]
    #11029705 -

There is most certainly a cross tolerance between phenethylamines and tryptamines. Although as long as your previous doses have been few and far between you should be ok at four days.


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"Jack thought it twice and thought that that had made it true. Some brains just work that way, that's what chemicals can do."


BTS

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Re: mushroom cross tolerance [Re: Shad0w]
    #11029723 -

Yes! There is a cross tolerance because they all affect your Serotonin 5HT2a receptor (Phenethylamines and tryptamines) . There is a cross tolerance between mushrooms cacti and LSD so you're going to need to make a choice


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He believed that educated people
could make up their own minds. His motto, as head of one of the first and
most important review panels, was great encouragement: "We're not here
to play God."

-DMT: The Spirit Molecule

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Re: mushroom cross tolerance [Re: Flowing]
    #11030754 -

hmm it seems im wrong..sorry  fatso


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Treasure Every Moment

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Re: mushroom cross tolerance [Re: rovert]
    #11031204 -

it might take about a week to har the cacti tar ready so i might itrip tonight if i feel up to it.


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My old Papaver Somniferums var. Gigantum and my Passion Flower...

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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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