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OfflinemotamanM
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Active Ingredients In Marijuana Found To Spread And Prolong Pain
    #10858289 - 08/14/09 09:11 AM (14 years, 9 months ago)

Active Ingredients In Marijuana Found To Spread And Prolong Pain

ScienceDaily (Aug. 14, 2009) — Imagine that you're working on your back porch, hammering in a nail. Suddenly you slip and hit your thumb instead — hard. The pain is incredibly intense, but it only lasts a moment. After a few seconds (and a few unprintable words) you're ready to start hammering again.

How can such severe pain vanish so quickly? And why is it that other kinds of equally terrible pain refuse to go away, and instead torment their victims for years?

University of Texas Medical Branch at Galveston researchers think they've found at least part of the answer—and believe it or not, it's in a group of compounds that includes the active ingredients in marijuana, the cannabinoids. Interestingly enough, given recent interest in the medical use of marijuana for pain relief, experiments with rodents and humans described in a paper published in the current issue of Science suggest these "endocannabinoids," which are made within the human body, can actually amplify and prolong pain rather than damping it down.

"In the spinal cord there's a balance of systems that control what information, including information about pain, is transmitted to the brain," said UTMB professor Volker Neugebauer, one of the authors of the Science article, along with UTMB senior research scientist Guangchen Ji and collaborators from Switzerland, Hungary, Japan, Germany, France and Venezuela. "Excitatory systems act like a car's accelerator, and inhibitory ones act like the brakes. What we found is that in the spinal cord endocannabinoids can disable the brakes."

To get to this conclusion, the researchers began by studying what happened when they applied a biochemical mimic of an endocannabinoid to inhibitory neurons (the brakes, in Neugebauer's analogy) on slices of mouse spinal cord. Electrical signals that would ordinarily have elicited an inhibitory response were ignored. They then repeated the procedure using slices of spinal cord from mice genetically engineered to lack receptors where the endocannabinoid molecules could dock, and found that in that case, the "brakes" worked. Finally, using electron microscopy, they confirmed that the receptors were in fact on inhibitory, not excitatory neurons. Endocannabinoids docking with them would suppress the inhibitor neurons, and leave pain signals with a straight shot to the brain.

"The next step was to make the leap from spinal slices to test whether this really had anything to do with pain," Neugebauer said. Using anesthetized rats, he recorded the spinal cord electrical activity produced by an injection in the hindpaw of capsaicin– a chemical found in hot peppers that produces a level of pain he compared to a severe toothache. Although the rats were unconscious, pain impulses could be detected racing up their spinal cords. What's more, formerly benign stimuli now generated a significant pain response — a response that stopped when the rats were treated with an endocannabinoid receptor blocker.

"Why was this non-painful information now gaining access to the spinal "pain" neurons?" Neugebauer said. "The capsaicin produced an overstimulation that led to the peripheral nerves releasing endocannabinoids, which activated receptors that shut down the inhibitor neurons, leaving the gates wide open."

Finally, the researchers recruited human volunteers to determine whether a compound that blocked endocannabinoid receptors would have an effect on the increased sensitivity to pain (hyperalgesia) and tendency for normally non-painful stimuli to induce pain (allodynia) often reported in areas of the body near where acute pain had been inflicted. In this case, the researchers induced pain by passing electricity through the volunteers' left forearms, with the intensity of the current set by each volunteer to a 6 on a scale of 1 to 10. At a second session a month later, the volunteers who had received the receptor blocker showed no reduction in perceived acute pain, but had significantly less hyperalgesia and allodynia — a result that matched up well with the endocannabinoid hypothesis.

"To sum up, we've discovered a novel mechanism that can transform transient normal pain into persistent chronic pain," Neugebauer said. "Persistent pain is notoriously difficult to treat, and this study offers insight into new mechanisms and possibly a new target in the spinal cord."

It also raises questions about the efficacy of marijuana in relieving acute pain, given that endocannabinoids and the cannabinoids found in marijuana are so biochemically similar. "If you had a toothache, you probably wouldn't want to treat it with marijuana, because you could actually make it worse," Neugebauer said. "Now, for more pathological conditions like neuropathic pain, where the problem is a dysfunction within the nerves themselves and a subsequent disturbance throughout the nervous system that's not confined to the pain system, marijuana may be beneficial. There are studies that seem to show that. But our model shows cannabinoids over-activating the pain system, and it just doesn't seem like a good idea to further increase this effect."

http://www.sciencedaily.com/releases/2009/08/090813170848.htm


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OfflineAsAboveSoBelow
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10858335 - 08/14/09 09:38 AM (14 years, 9 months ago)

I guess all medical-marijuana patients are conspiring together; cannabis in fact DOESNT help their pain, they're just saying it does in an attempt to legalize it!


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Offlinepasucks
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: AsAboveSoBelow]
    #10858364 - 08/14/09 09:48 AM (14 years, 9 months ago)

It also raises questions about the efficacy of marijuana in relieving acute pain

  Funny how this little sentence is at the end when in truth the whole discovery and article is to let you know marijuana is bad and shouldn't be used for medical purposes. :yawn:  the shits getting old and fact is Human Beings should be allowed to determine what and what not is helpful for them not some scientist.

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Offlineistandalone
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: pasucks]
    #10858431 - 08/14/09 10:12 AM (14 years, 9 months ago)

the first thing i thought of when i read this article was it seems to be somewhat true.
i remember when I'd go to the dentist to get a filling or whatever, and every time I'd go there high, the Novocain would have a minimal effect. if i was burnt, it never fails that the dentist has to double dose me in order for me to not feel pain.

maybe this is just coincidence, but i don't think so. also I'm not the only person that noticed this...there was a decent sized thread started about this very subject (dental drilling when high on pot hurting more) on grasscity forum.


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Now he's Johnny Hammersticks hammerin' away like he's friggin' Tommy Noble

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OfflineShamanintraining
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10858435 - 08/14/09 10:14 AM (14 years, 9 months ago)

The article has nothing to do with cannabis as they did not use THC for the study.  The title is bull shit.


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Offlinejoshisstoned
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Shamanintraining]
    #10858446 - 08/14/09 10:19 AM (14 years, 9 months ago)

i love how they try to refute my mothers claims that it helps her pain. She's my mother, the woman who taught me litterally how to wipe my ass, I think id believe her account and experiments over some douchebag. What kind of place are they running in galveston? Glad rats arent happy well guess what? I am! Pain free mother fucker! FTW!

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InvisibleSophistic Radiance
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10858677 - 08/14/09 11:37 AM (14 years, 9 months ago)

Misleading article, yes. I have personal experience proving that marijuana can relieve at least some kinds of pain.

All this article really says is that activity of the endocannabinoid system can amplify pain, so durr hurr hurr exocannabinoids would obviously amplify pain too. Because, you know, they don't do anything the endocannabinoid system doesn't already do. Stoners just have a pathological enjoyment of the feeling of inhaling burnt plant matter.


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OfflineEdgeChaos
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10858830 - 08/14/09 12:11 PM (14 years, 9 months ago)

I always thought those medical fans were bullshitting. Not that I care, I would love a nice legal loophole.

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OfflineDragonChaser
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10858876 - 08/14/09 12:18 PM (14 years, 9 months ago)

Quote:

Tchan909 said:
Misleading article, yes. I have personal experience proving that marijuana can relieve at least some kinds of pain.





I think that "some kinds" are the key words here.

I forget what the conditions are, like MS or whatever, where pain is being caused by nerve problems, or old injuries.  I believe herb can help with that.

But regular pain?  I've never noticed any lessening of pain while stoned.  When I get hurt while I'm stoned, it DOES seem to hurt more for me.  And getting stoned while you have a sunburn?

Fucking forget about it.  I hate being high when my back is all burnt up.


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OfflineCaladan_Shroom
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: DragonChaser]
    #10858958 - 08/14/09 12:30 PM (14 years, 9 months ago)

Scientific research has been proven to cause cancer in lab mice!!

Seriously though - How do they expect to isolate a few of the hundreds of active compounds in marijuana, spread it around on some mashed-up rodents and expect the world to believe that marijuana doesn't help with pain?

I personally have experienced pain relief with marijuana, but it's not the classic type of pain relief that I experience on opiate-based pain killers.  I'm aware of the pain.  I feel it.  It just doesn't feel like pain - if that makes any sense?

This is one of the reasons I like to partake before stretching or lifting weights.  I can feel every single little muscle fiber doing it's job. I can focus my attention lazer-like on the areas I am specifically trying to work.  I can definitely feel the burn - in fact, I'm more aware of it than ever, but it is eponentially more tolerable than without marijuana.  It doesn't "hurt".  It's just there...  Maybe this is what they are noticing when running their tests, but that is in no way conclusive of.... well, anything other than the fact that labratory experiments are bad for mice.  Go figure.

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InvisibleSophistic Radiance
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: DragonChaser]
    #10859056 - 08/14/09 12:46 PM (14 years, 9 months ago)

Nerve pain, yes. Sometimes I get stress pain that doesn't really come from any physical problem I'm having and herb clears that right up.

Besides, medical MJ's strongest selling point isn't its pain relief, but its anti-emetic and ocular activities. We have plenty of more effective drugs to treat pain, but not uncontrollable vomiting or glaucoma.

Personally I think it should be indicated for alcoholism too, but most establishment doctors would probably pull some BS out of their asses about how replacing one addiction with another blah blah blah. :rolleyes:

Remember: the man in the lab coat knows best.


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Offlinezenman223
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: AsAboveSoBelow]
    #10859078 - 08/14/09 12:51 PM (14 years, 9 months ago)

Quote:

AsAboveSoBelow said:
I guess all medical-marijuana patients are conspiring together; cannabis in fact DOESNT help their pain, they're just saying it does in an attempt to legalize it!




i think thats what alot of people in california ARE doing. dont get me wrong i believe it does have medicinal benefits like helping with nausea and appetite stimulation for chemo patients but ive always said its bullshit that marijuana relieves pain. now that being said just like the guy who's mom says it helps, i believe that being stoned can make you generally feel better than you did proir, especially if your really feeling terrible. of course getting high might make you FEEL BETTER but as far as analgesia IVE NEVER PERSONALLY noticed any such effects. ive have noticed if im really sick with a cold or flu and get high it actually makes me feel worse! this study doesnt suprise me at all.

and it doesnt matter they didnt use THC, they used other cannoibinoinds that mimic the ones found in marijuana. the study has nothing to do with THC'S effect on pain, its about MARIJUANA'S effect on pain!


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"I think I am, therefore I become."
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InvisibleSophistic Radiance
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: zenman223]
    #10859086 - 08/14/09 12:53 PM (14 years, 9 months ago)

This post makes no sense, good sir. THC is a rather important constituent of marijuana's pharmacological effects, last I checked. And also, all pain is not made alike.

I will personally beat the shit out of anybody who questions the legitimacy of marijuana as medicine. Bring it on.


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Enlil said:
You really are the worst kind of person.


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OfflineGrizzdude
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10859351 - 08/14/09 01:33 PM (14 years, 9 months ago)

This article is bullshit! Just another ploy from our government to tell people MJ is bad to keep it illeagal. Fact is it all started with the paper and oil industries in the 20's spent large amounts of money to produce false claims to get MJ illeagal. Oh but alcohol is much less harmful than weed right? Gimme a F'in break!

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Invisibledressel11
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10859368 - 08/14/09 01:36 PM (14 years, 9 months ago)

I'm no scientist so I'm not sure if how close endocannabinoids are to regular cannabinoids, but with around 60 active ones in the plant there is no reason the title should be labeled like it is. They did only take a few of them isolated and put them on the spine of mice. Thats something that will never happen when it's smoked.

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OfflineEdgeChaos
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10859457 - 08/14/09 01:49 PM (14 years, 9 months ago)

Cannabis should be treated like any other herbal remedy. making it a medical issue is silly.

It seems like the "medical" effects of cannabis are wildly unpredictable. some people get pain relief some people get nausea relief and some people get stress relief. just sounds like more of a herbal remedy than a medical treatment.

Any doctor who tells you to smoke anything for treatment is a quack.

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OfflineVibes
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: EdgeChaos]
    #10859924 - 08/14/09 02:52 PM (14 years, 9 months ago)

Depends on the pain you are suffering from.


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OfflinePoopSoap
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Vibes]
    #10860106 - 08/14/09 03:14 PM (14 years, 9 months ago)

95% of the time marijuana completely gets rid of my headaches. The only time it doesn't work is when I have a sinus headache from congestion or something. At the end of a long day at work my muscles are usually sore and it makes them feel like new again. If it doesn't get rid of pain I can't say that it makes it any worse.

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Invisiblegolden1
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PoopSoap]
    #10860881 - 08/14/09 05:24 PM (14 years, 9 months ago)

when I'm high pain feels the same or worse, but it makes pain more of a neutral feeling.
example: yes it hurts bad, but it doesn't matter now, I'M HIGH

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OfflinePeterGriffin467
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: golden1]
    #10861096 - 08/14/09 06:11 PM (14 years, 9 months ago)

Yea exactly I get no pain relief from weed it actualy seems to increase it if its any type of muscle pain or headache.


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OfflineMushroomTrip
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: pasucks]
    #10861189 - 08/14/09 06:56 PM (14 years, 9 months ago)

Quote:

pasucks said:
the shits getting old and fact is Human Beings should be allowed to determine what and what not is helpful for them not some scientist.




WHAT are you talking about? :what:
Where did the scientists say that you're NOT supposed to smoke pot?
Science CAN and DOES determine what effects a substance will have on your brain and how it will affect you, and it doesn't mean that one isn't free to do whatever they want. Grow the fuck up!  :bitchsmack:


--------------------
:bunny::bunnyhug:
All this time I've loved you
And never known your face
All this time I've missed you
And searched this human race
Here is true peace
Here my heart knows calm
Safe in your soul
Bathed in your sighs

:bunnyhug: :yinyang2:

Edited by MushroomTrip (08/14/09 07:18 PM)

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OfflineMushroomTrip
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10861238 - 08/14/09 07:08 PM (14 years, 9 months ago)

Quote:

Tchan909 said:
All this article really says is that activity of the endocannabinoid system can amplify pain, so durr hurr hurr exocannabinoids would obviously amplify pain too.




dur hur hur doesn't replace knowledge, it only makes your lack of knowledge even more embarrassing. :wink:

Quote:

Because, you know, they don't do anything the endocannabinoid system doesn't already do. Stoners just have a pathological enjoyment of the feeling of inhaling burnt plant matter.




The stupidity in your posts just gets bigger and bigger, doesn't it?
Please get over the anorexic girl drama and try to make sense.
Using the logic you've been using here, I could easily say that taking E doesn't make you feel more euphoric and doesn't increase your serotonin.

Quote:

Tchan909 said:
Nerve pain, yes. Sometimes I get stress pain that doesn't really come from any physical problem I'm having and herb clears that right up.

Besides, medical MJ's strongest selling point isn't its pain relief, but its anti-emetic and ocular activities. We have plenty of more effective drugs to treat pain, but not uncontrollable vomiting or glaucoma.

Personally I think it should be indicated for alcoholism too, but most establishment doctors would probably pull some BS out of their asses about how replacing one addiction with another blah blah blah. :rolleyes:

Remember: the man in the lab coat knows best.




What point are trying to make here? That these results are flawed? That marijuana does indeed help with pain relief, or are you just trying to say that marijuana has other beneficial properties, such as anti-nausea and such?
If it's the latter, then what's the problem with science debunking an old myth that states pot is wonderful against pain? Oh, I get it, it's too hard to accept science when it makes your beloved drug look bad.


--------------------
:bunny::bunnyhug:
All this time I've loved you
And never known your face
All this time I've missed you
And searched this human race
Here is true peace
Here my heart knows calm
Safe in your soul
Bathed in your sighs

:bunnyhug: :yinyang2:

Edited by MushroomTrip (08/14/09 07:17 PM)

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OfflineMushroomTrip
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Caladan_Shroom]
    #10861273 - 08/14/09 07:13 PM (14 years, 9 months ago)

Quote:

Caladan_Shroom said:
Scientific research has been proven to cause cancer in lab mice!!





Source?

Quote:

Seriously though - How do they expect to isolate a few of the hundreds of active compounds in marijuana, spread it around on some mashed-up rodents and expect the world to believe that marijuana doesn't help with pain?




Just because you personally can't understand how an experiment of this kind works, it doesn't mean that it is impossible to determine whether or not marijuana is helping with pain alleviation.

Quote:

Maybe this is what they are noticing when running their tests, but that is in no way conclusive of.... well, anything other than the fact that labratory experiments are bad for mice.  Go figure.




:whatever:


--------------------
:bunny::bunnyhug:
All this time I've loved you
And never known your face
All this time I've missed you
And searched this human race
Here is true peace
Here my heart knows calm
Safe in your soul
Bathed in your sighs

:bunnyhug: :yinyang2:

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Offlineastronaut
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PeterGriffin467]
    #10861551 - 08/14/09 08:04 PM (14 years, 9 months ago)

As skeptical as I am of anti-drug 'science', I have to agree 100% with what is said here. It always prolongs sudden acute pain (eg a stubbed toe) for me, and it makes other types of pain, like muscle aches and headaches, a lot more impeding. It also changes the sensation of pain in a way I find hard to describe. It feels a lot closer and personal. Maybe I've learned to dissociate pain in sobriety, and hash strips me of that programme, or maybe it has to do with the actual pharmacology... I don't know.

edit - actually I think it is more a matter of dissociation for me, as I have an incredible pain tolerance.

Edited by astronaut (08/14/09 08:13 PM)

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Offlinebanquet
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: astronaut]
    #10861623 - 08/14/09 08:16 PM (14 years, 9 months ago)

marijuana eases chronic pain in some people when they're high, and just like their tolerance increases, pain comes back. In some cases as the guy above me said marijuana makes acute pain last longer.

Synthetic cannaboids are another story all together, while trying spice gold, it triggered really bad headaches and i had to go to sleep.

Tolerance . tolerance. tolerance.

marijuana masks the pain but it doesn't cure it.

the worst thing about this experiment is that they're inducing pain on lab rats , when will they learn that they could be a rat in their next life, how would it feel if i inject pain in their spinal cord. idiots.


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Offlinexpaladoshes
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10861691 - 08/14/09 08:30 PM (14 years, 9 months ago)

The pain goes away when you are HIGH, So your mind is separated from the pain, the body is relaxed...and if you stay high the whole time your in pain, well then you will never feel it...did the experimenters isolate just certain cannabinoids or did they at least include THC with the experiment?

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OfflineLSDaytripper
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10861771 - 08/14/09 08:45 PM (14 years, 9 months ago)

Their test only used some of the compounds found In marijuana. Therefore it is incorrect to say that weed doesn't help pain because some compounds (thc included) were not tested and the combination of chemicals has a huge impact on how it affects you, not just the chemicals themselves.


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***** (10:42:46 PM): This is so strange
***** (10:42:53 PM): Becuase I feel that I am very altered
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OfflineAsAboveSoBelow
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: MushroomTrip]
    #10862651 - 08/14/09 11:43 PM (14 years, 9 months ago)

"Oh, I get it, it's too hard to accept science when it makes your beloved drug look bad."

Oh Listen to Bill Nye here, what side are you on anyway? It doesn't matter if the study is right. Any defender of liberty should oppose this article; it's just another thorn in the side of legalization.


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You're gonna get hurt real bad :smile:

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OfflineHighHat
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PeterGriffin467]
    #10863104 - 08/15/09 12:59 AM (14 years, 9 months ago)

Quote:

Remember: the man in the lab coat knows best.




Precisely why we should all go get our own degrees and lab coats so people start listening to US for a change.

Scientific Method FTW!


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Have you ever felt like you were wearing a hat, but you weren't?

"Those who would give up Essential Liberty to purchase a little Temporary Safety, deserve neither Liberty nor Safety" -Letter from the Pennsylvania Assembly, November 11, 1755

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Offlinesloppy
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10863228 - 08/15/09 01:25 AM (14 years, 9 months ago)

I've had chronic back pain and have been on high doses of Oxycontin, Fentynal, Dilaudid, and Methadone for 7 years. I stopped smoking weed because I would have muscle spasms in my back and the pain was worse. I started smoking again recently and it isn't giving me spasms anymore, but the pain don't go away it just doesn't seem to bother me as bad. I think it is different for each person, but it doesn't kill pain like a painkiller it just makes it tolerable.

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OfflineJive turkey
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10863329 - 08/15/09 01:59 AM (14 years, 9 months ago)

I've never noticed an increase in pain while being stoned at least not in acute pain actually just the opposite.

My girlfriend loves to pop my back pimples and I usually a scream like a little girl especially when she digs into one of those deep cyst-like bastards ,but if I get nice and baked first I just lay there and take it lol.

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InvisibleSophistic Radiance
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: MushroomTrip]
    #10863367 - 08/15/09 02:11 AM (14 years, 9 months ago)

I'm not trying to make a "point," I'm expressing my feelings regarding this particular article and the implications it may have in the popular debate regarding the legitimacy of medical marijuana. Kiss off back to P&S, or whatever bastardized form to which it has been reduced thanks to the propagation of the type of vapid pseudo-intellectual waste you have just defecated into this thread.


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Enlil said:
You really are the worst kind of person.


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Offlineorison
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Registered: 01/19/09
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PeterGriffin467]
    #10863569 - 08/15/09 03:27 AM (14 years, 9 months ago)

sorry but I agree with this, Im not going to deny the weed has some benefits. but theres been many as a zillion occasions after smoking marijuana my back pains and my arthritis gets worse.
but its only for few short moments , just the same the marijuana make them tolerable where my joints can crack and snap and feel way better.. i can ease into my exercise.. hell I have to take Oc's for pain that shit wears off the pain is 3xs worse, so I rather smoke more weed..
nobody should have the right to tell me what I can take.. Since I dont drink alcohol what other intoxicant can I enjoy.. Fuck this country and its house monkey..


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OfflineMushroomTrip
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: AsAboveSoBelow]
    #10863716 - 08/15/09 05:48 AM (14 years, 9 months ago)

Quote:

AsAboveSoBelow said:
"Oh, I get it, it's too hard to accept science when it makes your beloved drug look bad."

Oh Listen to Bill Nye here, what side are you on anyway? It doesn't matter if the study is right. Any defender of liberty should oppose this article; it's just another thorn in the side of legalization.




No, any defender of liberty and information should not give a damn about stupid stoner defense mechanisms and still accept the information, no matter how convenient or not it is.
A drug shouldn't be decriminalized because of how wonderful it is, but because everyone should be treated as responsible adults free to put whatever they want in their bodies, even if it kills them. If anything, people thinking like you are a major drawback in thinking and acting rationally.


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:bunny::bunnyhug:
All this time I've loved you
And never known your face
All this time I've missed you
And searched this human race
Here is true peace
Here my heart knows calm
Safe in your soul
Bathed in your sighs

:bunnyhug: :yinyang2:

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OfflineMushroomTrip
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Sophistic Radiance]
    #10863719 - 08/15/09 05:51 AM (14 years, 9 months ago)

Quote:

Tchan909 said:
I'm not trying to make a "point," I'm expressing my feelings regarding this particular article and the implications it may have in the popular debate regarding the legitimacy of medical marijuana. Kiss off back to P&S, or whatever bastardized form to which it has been reduced thanks to the propagation of the type of vapid pseudo-intellectual waste you have just defecated into this thread.




Wow, you're even stupider than the last time we talked.
Listen, I'll post wherever I want, and if you can't answer my questions you'll be the one who won't be able to tie a couple of words together in a rational sentence that can support your claims.
But, as I expected, there's nothing rational to support your thinking in this thread, and this is exactly why you got all flamed up and answered the way you did.


--------------------
:bunny::bunnyhug:
All this time I've loved you
And never known your face
All this time I've missed you
And searched this human race
Here is true peace
Here my heart knows calm
Safe in your soul
Bathed in your sighs

:bunnyhug: :yinyang2:

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InvisibleGreen_T
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: MushroomTrip]
    #10864201 - 08/15/09 10:28 AM (14 years, 9 months ago)

This is only ONE article on the effects of marijuana on ONE type of pain. Its not going to "kill the movement" or anything like that. All it suggests is that it increases the pain which travels along one kind of neuron, at the level recorded in the spinal chord. It doesn't say anything about the pain centers in the brain, and how it affects how we perceive pain.

If anything, this calls for more research on what types of pain it amplifies and if it inhibits other types of pain, the role of endocannabinoids in pain reception (why could amplification/awareness of certain types of pain/afferent nerve impulses be beneficial?), and why certain users swear by it's pain relieving properties, if it affects not just pain afferent neurons, etc.

Accepting articles which prove your view and rejecting ones which don't is called bias and is what creationists do, and it bugs me immensely.


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"I have sworn upon the altar of god eternal hostility against every form of tyranny over the mind of man" - Thomas Jefferson

Legalize Meth | Drug War Victims

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Offlineastronaut
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: MushroomTrip]
    #10864226 - 08/15/09 10:40 AM (14 years, 9 months ago)

Quote:

MushroomTrip said:
Quote:

AsAboveSoBelow said:
"Oh, I get it, it's too hard to accept science when it makes your beloved drug look bad."

Oh Listen to Bill Nye here, what side are you on anyway? It doesn't matter if the study is right. Any defender of liberty should oppose this article; it's just another thorn in the side of legalization.




No, any defender of liberty and information should not give a damn about stupid stoner defense mechanisms and still accept the information, no matter how convenient or not it is.
A drug shouldn't be decriminalized because of how wonderful it is, but because everyone should be treated as responsible adults free to put whatever they want in their bodies, even if it kills them. If anything, people thinking like you are a major drawback in thinking and acting rationally.




quoted for fucking truth. evidence precedes argument, not vice versa.

I like to think psychedelic users are generally more intelligent than the masses. maybe I'm living in a fantasy world ;-/

if marijuana were found to cause Parkinson's in 90% of users, AsAbove, would you try to silence that research in the interest of legalization? fuck that, man, you're no worse than thinktanks that stifle research into other hot-button issues. weed has enough going for it as far legalization goes, without you and your kind trying to censor the science of it.


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In another Time's Forgotten Space, your Eyes looked through your Mother's Face:
Wildflower Seed on the Sand and Stone, may the Four Winds blow you Safely Home!

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InvisibleDutchie3k
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PeterGriffin467]
    #10864303 - 08/15/09 11:17 AM (14 years, 9 months ago)

The whole point of TREATING pain is that most chronic pain sufferers have a condition that cannot be remedied/fixed easily, if at all, and therefore it makes sense to treat the pain itself so that it is less debilitating to the patient.

I can personally certify that any/all occurrence of my near-daily migraine headaches has ceased since I could get back to smoking fairly regularly.  & it's fun too huh? :laugh:


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"The Edge... there is no honest way to explain it because the only people who really know where it is are the ones who have gone over.  The others - the living - are those who pushed their control as far as they felt they could handle it, and then pulled back, or slowed down, or did whatever they had to when it came time to choose between Now and Later"

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Invisibletruffleupagus
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: motaman]
    #10864953 - 08/15/09 02:11 PM (14 years, 9 months ago)

I think pot definitely relieves some kinds of pain, like it was mentioned.

But I noticed when my back was bothering me, smoking weed would just make it worse.  I assumed it mainly had to do with it affecting my posture.

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Offlinejohnny.fairplay
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: truffleupagus]
    #10864969 - 08/15/09 02:14 PM (14 years, 9 months ago)

I think they should repeat the test with the same chemicals found in pot rather than "biochemically similar" ones, different chems act differently even if theyre structure is similar.  especially in the nervous system


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OfflineLSDaytripper
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: johnny.fairplay]
    #10865441 - 08/15/09 04:21 PM (14 years, 9 months ago)

And another thing. All drugs affect all people differently, so it's ridiculous to say that weed can't help anybodys pain or will help everyones pain. Bottom line is that doctors should give their patients the best possible treatment for their individual case, and if that happens to be weed, it should be legally available to patients.


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***** (10:42:46 PM): This is so strange
***** (10:42:53 PM): Becuase I feel that I am very altered
***** (10:42:57 PM): But at the same exact time
***** (10:43:28 PM): I am closer to the real me, the real me who decides who I am, the entire me

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InvisibleInvisible_Woe


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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: LSDaytripper]
    #10868529 - 08/16/09 03:01 AM (14 years, 9 months ago)

yeah i have chronic back pain, and smoking helps somewhat but honestly taking something like ibuprofen or an opiate helps more....and honestly i would lie to a doctor to get the MM script....or would i?


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OfflineKonyap


Registered: 06/30/07
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: Invisible_Woe]
    #10869574 - 08/16/09 10:33 AM (14 years, 9 months ago)

i was under the suspicion all drugs slow down recovery because your brain is never readily producing stuff of that way anyway so it needs to figure out a place for that stuff to go

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OfflinePeterGriffin467
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: johnny.fairplay]
    #10870140 - 08/16/09 12:40 PM (14 years, 9 months ago)

Why would you make your screen name after one of the biggest faggots to ever be on tv?


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OfflineKonyap


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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PeterGriffin467]
    #10870766 - 08/16/09 02:32 PM (14 years, 9 months ago)

<object width="425" height="344"><param name="movie" value="
name="allowFullScreen" value="true"></param><param name="allowscriptaccess" value="always"></param>

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Offlinealphasnail
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Re: Active Ingredients In Marijuana Found To Spread And Prolong Pain [Re: PeterGriffin467]
    #10875174 - 08/17/09 10:45 AM (14 years, 8 months ago)

This is awkward... Iv suffered from chronic back pain for many years, had 2 major surgerys, and im only 18 years old. Getting to my point, If it were not for use of Cannabis I would have dropped out of highschool. Im not saying that the rat is feeling more pain, ovcourse he is, they got his spine all cut up and shit while dripping chemicals on it.

However its not so much that the cannabis relieves the pain, It helps me keep my mind off it, so i can be more productive in so many ways and not so debilitated.

And I tried painkillers, never taking a opiate again. Nothing but bad comes out of them.

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