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MOTH
Wild Woman
Registered: 06/06/03
Posts: 23,431
Loc: In the jungle
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Monkey's that glow green actually exist now
#10410856 - 05/27/09 10:37 PM (14 years, 10 months ago) |
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From Reuters Newservice:
WASHINGTON (Reuters) – Japanese researchers have genetically engineered monkeys whose hair roots, skin and blood glow green under a special light, and who have passed on their traits to their offspring, the first time this has been achieved in a primate.
They spliced a jellyfish gene into common marmosets, and said on Wednesday they hope to use their colony of glowing animals to study human Parkinson's disease and amyotrophic lateral sclerosis or ALS.
Erika Sasaki and Hideyuki Okano of the Keio University School of Medicine in Japan used a virus to carry the gene for green fluorescent protein into monkey embryos, which were implanted into a female monkey, and four out of five were born with the gene throughout their bodies.
One fathered a healthy baby that also carried the new genes, they reported in Thursday's issue of the journal Nature.
"The birth of this transgenic marmoset baby is undoubtedly a milestone," stem cell expert Dr. Gerald Schatten, of the University of Pittsburgh School of Medicine, and Shoukhrat Mitalipov, of Oregon Health and Sciences University, wrote in a commentary in Nature.
"Transgenic marmosets are potentially useful models for research into infectious diseases, immunology and neurological disorders, for example," they wrote.
INCURABLE DISEASES
"I am most interested in Parkinson's disease and ALS," Okano told reporters in a telephone briefing. Both are incurable nerve diseases. But Okano said animals could be created to study a range of diseases.
The researchers used marmosets because they reproduce quickly, reaching sexual maturity in about a year.
"At the moment we use mice with mutant genes that are associated with Parkinson's to search for new drugs to treat the condition," Dr. Kieran Breen, director of Research and Development at Britain's Parkinson's Disease Society, said in a statement.
"Because non-human primates are much closer to humans than mice genetically, the successful creation of transgenic marmosets means that we will have a new animal model to work with."
Last year, the discoverers of the green fluorescent protein won the Nobel Prize in chemistry -- Japanese-born Osamu Shimomura of the Marine Biological Laboratory in Woods Hole, Massachusetts, Martin Chalfie of Columbia University in New York and Roger Tsien of the University of California, San Diego.
The protein glows under blue and ultraviolet light, allowing researchers to illuminate tumor cells, trace toxins and to monitor genes as they turn on and off.
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RandomHero
�.ǝןqısuodsǝɹɹı
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10410872 - 05/27/09 10:40 PM (14 years, 10 months ago) |
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this is crazy.
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Entropymancer
Registered: 07/16/05
Posts: 10,207
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10410887 - 05/27/09 10:43 PM (14 years, 10 months ago) |
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Old news. I'm pretty sure they came up with glow in the dark monkeys back around '05.
Still nuts though.
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MOTH
Wild Woman
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Re: Monkey's that glow green actually exist now [Re: RandomHero]
#10410888 - 05/27/09 10:43 PM (14 years, 10 months ago) |
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It's trippy to fathom how integrated genetic manipulation might increasingly become within our society over the next 100-200 years or so.
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MOTH
Wild Woman
Registered: 06/06/03
Posts: 23,431
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Re: Monkey's that glow green actually exist now [Re: Entropymancer]
#10410897 - 05/27/09 10:44 PM (14 years, 10 months ago) |
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Quote:
Entropymancer said: Old news.
New to me! And I'm sure others.
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MOTH
Wild Woman
Registered: 06/06/03
Posts: 23,431
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10410905 - 05/27/09 10:45 PM (14 years, 10 months ago) |
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WAIT A FREAKING MINUTE this isn't old news...
Quote:
WASHINGTON (Reuters) – Japanese researchers have genetically engineered monkeys whose hair roots, skin and blood glow green under a special light, and who have passed on their traits to their offspring, the first time this has been achieved in a primate.
Wed May 27, 7:28 pm ET
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I AM SWIM
doin' thangs
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10410910 - 05/27/09 10:46 PM (14 years, 10 months ago) |
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japanese really like the future, not only that but anything that glows is the future, and the future is now.
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Entropymancer
Registered: 07/16/05
Posts: 10,207
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10410923 - 05/27/09 10:48 PM (14 years, 10 months ago) |
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Ah, I see. The new news is that the glowing monkeys made glowing babies
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MOTH
Wild Woman
Registered: 06/06/03
Posts: 23,431
Loc: In the jungle
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Re: Monkey's that glow green actually exist now [Re: Entropymancer]
#10410950 - 05/27/09 10:53 PM (14 years, 10 months ago) |
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Quote:
Entropymancer said: Ah, I see. The new news is that the glowing monkeys made glowing babies
Indeed...good for them! Genetic engineering is really interesting to me. Have they made anything else really weird like this?
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Entropymancer
Registered: 07/16/05
Posts: 10,207
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10410987 - 05/27/09 11:00 PM (14 years, 10 months ago) |
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They've made all kinds of things glow in the dark. They really love that phosphorescent green chromophore gene. There's a similar gene that makes things glow red, but that hasn't been as widely messed-around with.
The main use for these glowing genes is to tie their expression to the production of specific other proteins, so we can see under a microscope where and when different proteins get made. I think the glowing animals are mostly for eye-candy. In fact, I know they have red- and green-glowing fish that they want to release commercially as a new line of pets
Most of the stuff they're dong with genetic engineering is more on the practical side, like getting yeast or E coli to mass-produce complicated proteins from other species so we can study them (synthesizing high yields of proteins is not really a practical approach, so we have other genetically-modified organisms do it for us).
And then there's Monsanto's line of sterile crops, so they can force farmers to buy new seeds every year rather than plant seeds from the harvest for the next season (that one really pisses me the hell off... I think it's currently working its way onto the market now).
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Gumby
Fishnologist
Registered: 06/13/01
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10411047 - 05/27/09 11:09 PM (14 years, 10 months ago) |
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I work with mice that have dopamine cells that glow green. They have a green rabbit too. I think Japan is responsible for that...
And pigs:
And mice/rats:
And fish:
You can actually buy "glo fish" in stores. They are genetically modified zebra danios. They are quite awesome. I plan to do an all green freshwater planted tank with black gravel full of the neon orange ones. I'll take pics of it if I ever get the money to do it. Those fish aren't cheap, about $6-$8 each. They are actually copyrighted and sterile so you can't breed them. They were originally created to be an indicator of polluted water sources.
They were supposed to turn orange in the presence of pollutants because they are very easy to see in dark water when they are orange. Not sure what ever happened with that.
The way science is going now, you can put GFP into almost any animal's genome to make them glow green under the right spectrum of light. Crazy shit. Genetics research is getting insane. I could go into the details of how my lab genetically engineered a virus to label cells, but that might compromise their research. So I'll shut up.
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Cubie
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Re: Monkey's that glow green actually exist now [Re: Gumby]
#10411087 - 05/27/09 11:13 PM (14 years, 10 months ago) |
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I cant wait for glowing humans!
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Set
candy colored clown
Registered: 10/03/08
Posts: 6,383
Loc: right near da beach
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10411128 - 05/27/09 11:19 PM (14 years, 10 months ago) |
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Let's not forget the transparent frog..
Oh, those Japanese.
-------------------- classic LOVELINE
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DepthToTheCore
JeeBuzz
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Posts: 3,649
Loc: Australia brah
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Re: Monkey's that glow green actually exist now [Re: Set]
#10411160 - 05/27/09 11:25 PM (14 years, 10 months ago) |
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The Japanese are on a completely different level, i can't wait to go there next year.
12,400 7/11's, beat that.
-------------------- "Those who dance are considered insane by those who cannot hear the music." - George Carlin
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learningtofly
Ancient Aliens
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Re: Monkey's that glow green actually exist now [Re: Set]
#10411170 - 05/27/09 11:26 PM (14 years, 10 months ago) |
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The Simpsons already did it.
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Set
candy colored clown
Registered: 10/03/08
Posts: 6,383
Loc: right near da beach
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Re: Monkey's that glow green actually exist now [Re: DepthToTheCore]
#10411193 - 05/27/09 11:30 PM (14 years, 10 months ago) |
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I lived in Yokohama for 3 weeks with a host family, it was bananas.
What was really cool is we stayed at their grandparent's villa on Mt. Fuji in the woods for a few days. That was fucking !
You'll have a blast there man!
-------------------- classic LOVELINE
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DepthToTheCore
JeeBuzz
Registered: 05/05/04
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Re: Monkey's that glow green actually exist now [Re: Set]
#10411214 - 05/27/09 11:33 PM (14 years, 10 months ago) |
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Oh man im so exicted, my girlfriend just went there for 2.5 weeks, and now we are going together next year.
Im sooooo pumped for the food, i've heard its INSANE.
Did you go to one of the 7/11's? My girlfriend tells me they are like mini-supermarkets, stocked every 24 hours with the freshest and most delicious food ever.
I can't wait!
-------------------- "Those who dance are considered insane by those who cannot hear the music." - George Carlin
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Cubie
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Re: Monkey's that glow green actually exist now [Re: DepthToTheCore]
#10411259 - 05/27/09 11:38 PM (14 years, 10 months ago) |
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7/11.. fresh.......... lol
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Set
candy colored clown
Registered: 10/03/08
Posts: 6,383
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Re: Monkey's that glow green actually exist now [Re: DepthToTheCore]
#10411270 - 05/27/09 11:40 PM (14 years, 10 months ago) |
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lol dude it's awesome
Nah, never went to a 7-11 there (that I remember, anyway). The grocery stores there are hilarious though! There's a giant section reserved for rice . The candy aisle is awesome, Japan definitely has the edge on sweets.
Food in Japan is amazing if you love seafood.
-------------------- classic LOVELINE
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DepthToTheCore
JeeBuzz
Registered: 05/05/04
Posts: 3,649
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Re: Monkey's that glow green actually exist now [Re: Cubie]
#10411279 - 05/27/09 11:41 PM (14 years, 10 months ago) |
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Im not kidding.
The food in 7/11's here are a disgrace, but over there its apparently completely different.
Looks pretty good to me, the dude at the counter even heats it up for you.
Win.
-------------------- "Those who dance are considered insane by those who cannot hear the music." - George Carlin
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circularvortex
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10411281 - 05/27/09 11:41 PM (14 years, 10 months ago) |
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Quote:
MOTH said: Monkey's that glow green actually exist now
Well it's about damn time!
-------------------- No statements made in any post or message by myself should be construed to mean that I am now, or have ever been, participating in or considering participation in any activities in violation of any local, state, federal, or fashion police laws. All posts are works of fiction. For well you know that its a fool who plays it cool By making his world a little colder. Under closer inspection I realised it was a funky ball of tits from outer space.
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DepthToTheCore
JeeBuzz
Registered: 05/05/04
Posts: 3,649
Loc: Australia brah
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Re: Monkey's that glow green actually exist now [Re: Set]
#10411284 - 05/27/09 11:42 PM (14 years, 10 months ago) |
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Quote:
Set said: lol dude it's awesome
Nah, never went to a 7-11 there (that I remember, anyway). The grocery stores there are hilarious though! There's a giant section reserved for rice . The candy aisle is awesome, Japan definitely has the edge on sweets.
Food in Japan is amazing if you love seafood.
Yeah man, seafood is the bomb, quality seafood that is.
One whole section reserved for rice?!?! How many varieties can there be?
-------------------- "Those who dance are considered insane by those who cannot hear the music." - George Carlin
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Set
candy colored clown
Registered: 10/03/08
Posts: 6,383
Loc: right near da beach
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Re: Monkey's that glow green actually exist now [Re: DepthToTheCore]
#10411340 - 05/27/09 11:52 PM (14 years, 10 months ago) |
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Quote:
DepthToTheCore said: Yeah man, seafood is the bomb, quality seafood that is.
One whole section reserved for rice?!?! How many varieties can there be?
There's a lot of "fast food" seafood, meaning not quite as fresh as you'd get in a Japanese restaurant in the US. Not to say that there isn't awesome/fresh seafood to be had there, just that seafood is so common that it's nowhere near the specialty that it is in the states.
As for the rice...it's pretty much the staple of their diet so it has a load of attention given to it (entertaining in my western eyes )
sorry to jack your thread, Moth
-------------------- classic LOVELINE
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Gumby
Fishnologist
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Posts: 26,656
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Re: Monkey's that glow green actually exist now [Re: Set]
#10411465 - 05/28/09 12:19 AM (14 years, 10 months ago) |
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Quote:
Set said: Let's not forget the transparent frog..
Oh, those Japanese.
That has nothing to do with the Japanese. Those frogs are 100% natural. There are a hell of a lot of animals that are transparent/translucent. Mainly amphibians and fish.
You can get these guys in most specialty fish stores (they're freshwater too):
Fish pictured in order: Glassfish Glass Catfish Blind Cave Tetra
If you EVER see any of these fish with insane neon colors, never buy them. Some sick fucks will sometimes inject these fish with neon colored dye to increase their selling potential. It's a disgusting practice that usually ends up with a 60%-75% death rate. I've read that the needle they use to inject them is equivalent to a human getting injected with a needle that is the size of a pencil. Fucked up. I shun any fish store that carries dyed fish.
Here are a dyed fish:
They probably died within two weeks of that picture being taken.
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Phish_Dude
steppin' into yesterday
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#10411584 - 05/28/09 12:53 AM (14 years, 10 months ago) |
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I'm usually against genetically modifying animals but thats just fucking sweet!
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StonedImmaculate
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Re: Monkey's that glow green actually exist now [Re: MOTH]
#11422683 - 11/09/09 09:45 PM (14 years, 5 months ago) |
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So, Parkinson's is incurable. It's in your dna, right? That means with genetic engineering that only the next generation will be saved.
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Entropymancer
Registered: 07/16/05
Posts: 10,207
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Re: Monkey's that glow green actually exist now [Re: StonedImmaculate]
#11422831 - 11/09/09 10:05 PM (14 years, 5 months ago) |
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1.) 5 month old thread
2.) Ever heard of gene therapy?
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Phate
Hmm...
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Re: Monkey's that glow green actually exist now [Re: StonedImmaculate]
#11422977 - 11/09/09 10:25 PM (14 years, 5 months ago) |
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Quote:
StonedImmaculate said: So, Parkinson's is incurable. It's in your dna, right? That means with genetic engineering that only the next generation will be saved.
You're missing the point.
and yea holy shit way to necro this thread
-------------------- Think for yourself, question authority.
Edited by Phate (11/09/09 10:26 PM)
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Gumby
Fishnologist
Registered: 06/13/01
Posts: 26,656
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Re: Monkey's that glow green actually exist now [Re: StonedImmaculate]
#11422999 - 11/09/09 10:28 PM (14 years, 5 months ago) |
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Quote:
StonedImmaculate said: So, Parkinson's is incurable. It's in your dna, right? That means with genetic engineering that only the next generation will be saved.
Not necessarily. Parkinson's could potentially be curable if they could figure out just why the hell the dopamine neurons in the substantia nigra start to die out. Sure, it's probably in your genetics for those cells to die out, but perhaps they're dying out because they're not getting the proper nutrients or something along those lines.
I worked in a lab that researched dopaminergic and GABAergic neurons of the substantia nigra, and I can tell you one thing: we have A LOT to learn about Parkinson's before it is curable. On the upside, there are literally hundreds, if not thousands, of labs working on understanding how the disease works. Once they understand how it works then they can start working on a cure.
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