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InvisibleveggieM

Registered: 07/25/04
Posts: 17,538
FDA issues warning for 'gas station heroin' as adverse reports rise
    #28634053 - 01/25/24 06:25 AM (3 months, 22 days ago)

FDA issues warning for 'gas station heroin' as adverse reports rise
January 24, 2024 - ABC

Products with tianeptine, marketed as an antidepressant and often sold under brand Neptune's Fix, have been reported to cause seizures and even death.

The U.S. Food and Drug Administration has issued a renewed warning against the purchase or use of any products containing tianeptine, commonly referred to as "gas station heroin," just under a week after lawmakers urged the federal body to take action against its use.

Tianeptine is an approved antidepressant in some countries, but not in the U.S. However, it continues to be sold here under brand names like Neptune's Fix, Tianna and Zaza online and at convenience stores and gas stations under the guise of being a health-improvement supplement.

The FDA first warned about tianeptine products, specifically from Neptune's Fix, in November, and late Tuesday, the federal agency said it continues to receive reports of the products causing adverse effects, including seizures, loss of consciousness and death.

Not only are they continuing, but reports of bad reactions and unwanted side effects involving tianeptine are rising nationwide. According to the FDA, total poison control center cases increased from just 13 between 2000 to 2013 to 151 cases in 2020 alone.

Regulators say consumers are drawn to purchase tianeptine products due to companies often marketing them as treatments to "improve brain function and treat anxiety, depression, pain, opioid use disorder, and other conditions."

But the FDA warns the products can interact with other medications in a consumer's body, including other antidepressants or anti-anxiety medications, and cause bad reactions.

Additionally, the CDC points to evidence showing tianeptine abuse and withdrawal can mimic opioid toxicity and withdrawal. This point was also made in a Jan. 18 letter signed by five bipartisan House representatives urging the FDA to more tightly regulate tianeptine due to its "opioid-like qualities."

The FDA says those with a history of opioid use or dependence may be at an increased risk of abusing tianeptine, and that abuse can cause harmful effects including drowsiness, rapid heartbeat, high blood pressure, vomiting, slowed or stopped breathing and more.

"People seeking to treat their ailments sometimes mistake a product as being safe because it's easily available, whether online or even at gas stations," the FDA said. "But availability is no indication of effectiveness or safety. This is especially true of tianeptine, an unapproved drug associated with serious health risks and even death."

Though the FDA does not approve dietary supplements for safety and effectiveness before they're sold to the public, it said Tuesday that Neptune Resources — the maker of Neptune's Fix — has now agreed to voluntarily recall three of its tianeptine products. It also said it sent a letter to convenience stores, gas stations and other organizations on Jan. 11, urging them to stop selling Neptune's Fix and any other tianeptine-containing products.

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InvisibleHolybullshit
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Registered: 01/06/19
Posts: 1,576
Re: FDA issues warning for 'gas station heroin' as adverse reports rise [Re: veggie] * 1
    #28634109 - 01/25/24 07:41 AM (3 months, 22 days ago)

I think they're exaggerating a little bit when it comes to the dangers and its utility as a recreational drug.

Kratom > tianeptine

And they could easily stop the sale of tianeptine in dietary supplements if they wanted to... It's not natural, and it definitely wasn't grandfathered in.

Though I can't say I'm disappointed that they seem to be more inclined to allow synthetic ingredients in dietary supplements.

Personally, I do my research. Though the shift in policy is likely to result in more harm, just not to me.

The problem with tianeptine is the high is so fleeting and tolerance builds so quickly. If you are at the point where you experience withdrawals it's pretty useless... I'd go so far as to say trying to use it as a maintenance drug is a grueling experience.

It's basically only useful as something to get by until your your dealer comes through. Or an every now and again thing for opioid naive individuals. And in both cases kratom is better.

It can get dangerous for people who are addicted and dependent on opioids and it's their only option and they are determined to use it for more than just staving off withdrawals.

Even IVing pure powder doesn't address its wants.

Edited by Holybullshit (01/25/24 07:53 AM)

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Invisibledurian_2008
Cornucopian Eating an Elephant
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Registered: 04/02/08
Posts: 18,037
Loc: Raccoon City
Re: FDA issues warning for 'gas station heroin' as adverse reports rise [Re: Holybullshit]
    #28634551 - 01/25/24 02:02 PM (3 months, 21 days ago)



The research chemical tianeptine is known to act upon opiate channels, is a serotonin reuptake enhancer (SSRE), and may stimulate cognitive function.

It is not especially clear how the overall balance of serotonin is affected, as compared to an SSRI, that affects impulsivity and even digestion.

However, MAOI's and tyramine (in your lunch) may putatively interact with any drug that affects the serotonin channels, causing hypotensive or hypertensive or manic episodes, in this case, on the road.

Police yourself.

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Offlinethirtygoats
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Registered: 12/29/11
Posts: 1,992
Last seen: 2 months, 20 days
Re: FDA issues warning for 'gas station heroin' as adverse reports rise [Re: veggie]
    #28635244 - 01/26/24 05:30 AM (3 months, 21 days ago)

Yet another drug (soon to be) banned because a minority/small number of people overuse it and experience adverse or unwanted effects. How many drugs have been banned because a tiny number of people overuse them? Probably the majority of illegal drugs. Obviously there are some drugs like bath salts that should never be legal or easily accessible, because obviously if you overuse a drug and eating other people's faces might become a possibility, that's a huge problem and shouldn't be ignored.

I've used Tianeptine before and I didn't experience anything horrible that would make me want to avoid it completely, or think that it should be illegal.

In a society or civilization where everyone is unhealthy, I would bet that 90% or more of all drugs would probably cause unwanted or adverse effects, even at a medium or small amount/dose used.

But I believe that people who are consciously always trying to improve their health, physically by eating healthy as often as possible and exercising as often as necessary, would be not only able to manage their drug use but stop their drug use if need be, and they would also be able to be aware if the drug is causing them to do things that they regret. They would even be able to improve themselves because of using a drug, as I have many times before. Even with heroin and meth, I was able to improve myself and I noticed that they improved me physically and mentally. I could exercise while high on heroin, I felt full of energy and very strong. I could eat healthy.

I know that I would not have experienced any of these improvements from using these drugs if I had been unhealthy and not taking care of myself.

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Invisibledurian_2008
Cornucopian Eating an Elephant
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Registered: 04/02/08
Posts: 18,037
Loc: Raccoon City
Re: FDA issues warning for 'gas station heroin' as adverse reports rise [Re: thirtygoats]
    #28635567 - 01/26/24 12:15 PM (3 months, 20 days ago)

A statistically-significant percentage of people die from taking prescriptions as prescribed, formally.

Without the color of authority, what would an SSRE do to me? :shrug:

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