Posted by kinaa11 (11/01/10 12:11 AM)
After you take shrooms, what is the recommended time you should wait until you take them again?
Posted by andyistic (01/27/09 12:27 AM)
Psilocybin is asorbed into the blood, then it passes through the liver, where it is converted to psilocin.
The conversion takes place in the liver, not the digestive system.
Posted by agelessbeauty (08/29/08 08:50 PM)
chalart.

everything you just said, makes sense. wow. thats amazing how that works. once again, my mind is blown.
Posted by chalart (05/11/08 12:24 AM)
I took a  neurology, physiology and behavior class last quarter called Illusions and the Brain. We learned that the way the body hallucinates from shrooms/acid is that when your brain is flooded with serotonin or molecules that resemble it (LSD/Psylocin), most of it is getting processed in a gland called the Raphe Nuclei. When this happens it is cutting off the stream of visual information to your optic nerve. You have visuals because your brain isn't recieving enough external information (auditory, visual etc..) and therefor decides to compensate for that loss by making its own crazy ass shit up.  You pretty much have hallucinations any time your brain isn't receiving as much information as it wants because this is your minds way of figuring out the world as best as it can. This happens all the time in gradual onset blindness as well.
After learning this, my trips have only gotten crazier.
Posted by JoelKl1 (04/07/08 11:03 PM)

I was going to edit this but then realized the information I was going to add from wikipedia needed a citation but here is the link and my copy paste skills.

 

"Psilocybin is rapidly dephosphorylated in the body to psilocin which then acts as a partial agonist at the 5-HT2A serotonin receptor in the brain where it mimics the effects of serotonin (5-HT). Psilocin is an 5-HT1A and 5-HT2A/2C agonist"

which means psilocin is also being taken up by theese other receptor sites and correcting 5-HT2 to 5-HT2a.

 

http://en.wikipedia.org/wiki/Psilocybin


Edited 4/7/2008 10:03 PM
Posted by Lyadin (03/10/08 03:41 AM)
From watching other people trip I have noticed they dont interact with the "real world" as much as they normally do. I understand that the chemicals in magic mushrooms affect different chemical receptors, but what I believe is going on (much with the case of salvia) the person undergoing the induced "trip" is more or less dreaming while they are awake. The information from their subconcious is overpowering their normal input receptors (i.e. eyes, nose, mouth, touch sense etc.) Maybe thats why they can produce somewhat "bad trips", kind of along the lines of a nightmare while you are awake. This may be why magic mushrooms are used in spiritual practices, because your concious mind can interprate what the unconcious is coming up with.

I don't know, just a guess, but if anyone reads this you can e-mail me on the subject.