No matter how experienced you are with tripping, please pick a few (any) of these Essential Links and read them from start to finish... unless you've already read them.
The Psychedelic experience often shows us the inner workings of our psyche. If you're even half interested in psychology and are familiar with experiments, theory, and philosophy you probably become hyperaware of these theories in your experience with psychedelics.
Using the data for rats and accepting a median of 1% potency, it would require the consumption of 1680g of mushrooms to reach the LD50 for a 60kg "rat".
The answer to this question is not a simple yes or no, however for the average person with no emotional or psychological problems or any family history of mental illness the answer is surely an un-equivocal no.
A "Trip Sitter" can be a very helpful person to have around especially if this person is naturally laid back and has experience with psychedelics and trippers.