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jimbotron said:
IMO only thing that matters is what happens when you run out -- do you go find more, or just shrug your shoulders.

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mtichael said:
women are the cure for insomnia 
i sleep a good extra 1500 hours cuz my wife is sleepin all the time

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That doesn't make any sense. I'd be awake, staring at her in her sleep, from the vantage point of 3 inches away from her face

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Humility said:
Hey Leopardman, don't you go talking about the love in my life!

I smoke weed every SINGLE day.  It has it's positives and negatives.  I think breaks are important and so I take one every month or so, but for the most part I'm high most of the day.

It's great.  HUGE moneysink, but if you can make supply a non-issue there's no reason not to smoke every day.

Like brother Zaka said, don't run out .

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Like I said, this is my experience. How old are you? I bet you are 20 or so. How long have you been smoking every single day of your life? If you go on like this, I am sure you will change your mind soon. I like weed, mushrooms and alcool: not a good reason to use them every day. Anyway enjoy your weed man!

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LeopardMan said:



Like I said, this is my experience. How old are you? I bet you are 20 or so. How long have you been smoking every single day of your life? If you go on like this, I am sure you will change your mind soon. I like weed, mushrooms and alcool: not a good reason to use them every day. Anyway enjoy your weed man!

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Cloudkicker said:
depends on the user, YOU CANNOT GET PHYSICALLY ADDICTED TO THE CANNABIS PLANT, but you can become psychologically addicted. Cocaine addiction and alcoholics have a mostly physical addiction where they need the drug to go on with their day.

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-Withdrawal
-Tolerance
-Difficulty controlling use
-Negative Consequences
-Neglecting activities that were once important to you
-Spending excessive money, time, and energy to obtain
-Unsuccessful desires or attempts to cut back use

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-Withdrawal....never stop!
-Tolerance......Bigger spliffs!
-Difficulty controlling use.....learn to roll perfect spliffs under any condition, no matter how wasted.
-Negative Consequences.....Huh?
-Neglecting activities that were once important to you,...Fuck it roll another!
-Spending excessive money, time, and energy to obtain....Hour of work farming does pay off.
-Unsuccessful desires or attempts to cut back use.....why? when you can have constant harvest?
Respect
Z

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deCypher said:
Not if you can stop without any problems. 

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I AM SWIM said:
Well with stuff like coke and crack, I would say that is more of a severe psychological addiction, and alcohol, benzos/barbs, opiates are more physical addiction.


Coke and Crack really will bring the demon out of the user, they are so powerful psychologically, that the user isn't really themselves anymore, so they will fuck over their friends and family just to get the drug.

It's too bad, because it feels so good, but I just can't control myself when I'm on those kind of dr00gz,


besides with dr00gz like coke, it makes you

but then when it wears off, it makes you


why would someone pay money to ??

that is backwards, weed

is only , unless a smokes weed, then it's not the weeds fault, only s fault

and in that case, more than likely, if smokes weed, chances are he will transform into

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Samurai Drifter said:

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jimbotron said:
IMO only thing that matters is what happens when you run out -- do you go find more, or just shrug your shoulders.

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Wanting to find more doesn't mean you have an addiction. That's like saying that I have an addiction to books if I want to buy a new one after I've read all of the ones I own. It's just something I enjoy, not something I *have* to do.

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boboandbaba said:
Cannabis is less dangerous than alcohol, nicoine and your favorite junk food. It causes NO negative side effects. BUT! Heavy weed users can be depressed, paranoid, stressed. WHY? Because marihuana ( like other drugs including alcohol)makes our brains produce more serotonin ( neurotransmitter which controls our sleep and mood. Nootrops, like 5-htp (5-hydroxytryptamine  i suppose), piracetam (because it helps our brains to produce 5-htp) are good things to help our nervous system to not be affected by any drugs side effects. Its like a shield, of course it can be ruined too). So, while mj ( or other drugs) helps to produce a huge amounts of serotonin, at the same time it ruins our brain ability to produce serotonin while we are not on drug. And when u are not on drug, u can be depressed and etc. That makes our brains ( not physical dependence but psichological) think that they need something what can produce serotonin. Neuroscience


But there is aother BUT. U need nootrops to restore your nervous system and of course a lot of milk and fresh air because it harms your lungs (especially smoking with tobbacco). that's all. And all side effects are more comming from tobbacco.

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The pharmacological actions of THC result from its binding to the cannabinoid receptor CB1, located mainly in the central nervous system, and the CB2 receptor, mainly present in cells of the immune system. It acts as a partial agonist on both receptors, i.e., it activates them but not to their full extent. The psychoactive effects of THC are mediated by its activation of the CB1 receptor, which is the most abundant G protein-coupled receptor in the brain.
The presence of these specialized receptors in the brain implied to researchers that endogenous cannabinoids are manufactured by the body, so the search began for a substance normally manufactured in the brain that binds to these receptors, the so-called natural ligand or agonist, leading to the eventual discovery of anandamide, 2-arachidonyl glyceride (2-AG), and other related compounds known as endocannabinoids. This story resembles the discovery of the endogenous opiates (endorphins, enkephalins, and dynorphin), after the realization that morphine and other opiates bind to specific receptors in the brain. In addition, it has been shown that cannabinoids, through an unknown mechanism, activate endogenous opioid pathways involving the ?1 opioid receptor, precipitating a dopamine release in the nucleus accumbens. The effects of the drug can be suppressed by the CB1 cannabinoid receptor antagonist rimonabant (SR141716A) as well as opioid receptor antagonists (opioid blockers) naloxone and naloxonazine.[12]
The mechanism of endocannabinoid synaptic transmission is thought to occur as follows: First, transmission of the excitatory neurotransmitter glutamate causes an influx of calcium ions into the post-synaptic neuron. Through a mechanism not yet fully understood, the presence of post-synaptic calcium induces the production of endocannabinoids in the post-synaptic neuron. These endocannabinoids (such as anandamide), then, are released into the synaptic cleft, where binding occurs at cannabinoid receptors present on pre-synaptic neurons, where they modulate neurotransmission. Thus, this form of neurotransmission is termed retrograde transmission, as the signal is carried in the opposite direction of orthodox propagation, which previously was thought to be exclusively one way.
THC has mild to moderate analgesic effects, and cannabis can be used to treat pain. The mechanism for analgesic effects caused directly by THC or other cannabinoid agonists is not fully understood. Other effects include relaxation; euphoria; altered space-time perception; alteration of visual, auditory, and olfactory senses; anxiety; disorientation; fatigue; and appetite stimulation (colloquially known as "the munchies"). The mechanism for appetite stimulation in subjects is believed to result from activity in the gastro-hypothalamic axis. CB1 activity in the hunger centers in the hypothalamus increases the palatability of food when levels of a hunger hormone ghrelin increase as food enters the stomach. After chyme is passed into the duodenum, signaling hormones such as cholecystokinin and leptin are released, causing reduction in gastric emptying and transmission of satiety signals to the hypothalamus. Cannabinoid activity is reduced through the satiety signals induced by leptin release. It also has anti-emetic properties, and also may reduce aggression in certain subjects.
THC has an active metabolite, 11-Hydroxy-THC, which may also play a role in the analgesic and recreational effects of cannabis.
The ?7 nicotinic receptor antagonist methyllycaconitine can block self-administration of THC in rats comparable to the effects of varenicline on nicotine administration.[13][14]

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