|
 wre
 
Registered: 05/06/09
Posts: 333
Loc: New Zealand
Last seen: 27 days, 9 hours
|
 Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers   3
#16876907 - 09/19/12 10:08 PM (8 months, 24 days ago) |
|
|
http://www.huffingtonpost.com/2012/09/19/marijuana-and-cancer_n_1898208.html
A pair of scientists at California Pacific Medical Center in San Francisco has found that a compound derived from marijuana could stop metastasis in many kinds of aggressive cancer, potentially altering the fatality of the disease forever.
"It took us about 20 years of research to figure this out, but we are very excited," said Pierre Desprez, one of the scientists behind the discovery, to The Huffington Post. "We want to get started with trials as soon as possible."
The San Francisco Chronicle first reported on the finding, which has already undergone both laboratory and animal testing, and is awaiting permission for clinical trials in humans.
Desprez, a molecular biologist, spent decades studying ID-1, the gene that causes cancer to spread. Meanwhile, fellow researcher Sean McAllister was studying the effects of Cannabidiol, or CBD, a non-toxic, non-psychoactive chemical compound found in the cannabis plant. Finally, the pair collaborated, combining CBD and cells containing high levels of ID-1 in a petri dish.
"What we found was that his Cannabidiol could essentially 'turn off' the ID-1," Desprez told HuffPost. The cells stopped spreading and returned to normal.
"We likely would not have found this on our own," he added. "That's why collaboration is so essential to scientific discovery."
Desprez and McAllister first published a paper about the finding in 2007. Since then, their team has found that CBD works both in the lab and in animals. And now, they've found even more good news.
"We started by researching breast cancer," said Desprez. "But now we've found that Cannabidiol works with many kinds of aggressive cancers--brain, prostate--any kind in which these high levels of ID-1 are present."
Desprez hopes that clinical trials will begin immediately.
"We've found no toxicity in the animals we've tested, and Cannabidiol is already used in humans for a variety of other ailments," he said. Indeed, the compound is used to relieve anxiety and nausea, and, since it is non-psychoactive, does not cause the "high" associated with THC.
While marijuana advocates will surely praise the discovery, Desprez explained that it's not so easy as just lighting up.
"We used injections in the animal testing and are also testing pills," he said. "But you could never get enough Cannabidiol for it to be effective just from smoking."
Furthermore, the team has started synthesizing the compound in the lab instead of using the plant in an effort to make it more potent.
"It's a common practice," explained Desprez. "But hopefully it will also keep us clear of any obstacles while seeking approval."
|
Jvells
Some asshole
Registered: 11/05/09
Posts: 1,650
Loc: CT 
Last seen: 18 hours, 21 minutes
|
 Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: wre]
#16877025 - 09/19/12 10:26 PM (8 months, 24 days ago) |
|
|
Scoree
--------------------
|
 psyconaught
Chemical Connoisseur
Registered: 11/04/10
Posts: 2,244
Loc: southern oregon
Last seen: 3 minutes, 34 seconds
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: Jvells]
#16877147 - 09/19/12 10:48 PM (8 months, 24 days ago) |
|
|
did we really just discover the cure to cancer in marijuana?  kick ass 
--------------------
Think for yourself, question authority
|
 Gilgamesh18
Registered: 03/01/12
Posts: 3,836
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: psyconaught]
#16877198 - 09/19/12 10:57 PM (8 months, 24 days ago) |
|
|
Il bet these scientists will suffer some unfortunate accidents in the weeks to come. 
--------------------
|
psyconaught
Chemical Connoisseur
Registered: 11/04/10
Posts: 2,244
Loc: southern oregon
Last seen: 3 minutes, 34 seconds
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: Gilgamesh18]
#16877213 - 09/19/12 10:59 PM (8 months, 24 days ago) |
|
|
Quote:
Gilgamesh18 said:
Il bet these scientists will suffer some unfortunate accidents in the weeks to come.
the whole project will probably be mothballed 
--------------------
Think for yourself, question authority
|
Humility
Working on it
Registered: 10/07/08
Posts: 6,696
Last seen: 7 days, 21 hours
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: psyconaught] 1
#16877341 - 09/19/12 11:24 PM (8 months, 24 days ago) |
|
|
Don't forget cannabis lowers your IQ and is carcinogenic and is highly dangerous.
Fucking lying pieces of shit. 
--------------------
 
|
psyconaught
Chemical Connoisseur
Registered: 11/04/10
Posts: 2,244
Loc: southern oregon
Last seen: 3 minutes, 34 seconds
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: Humility]
#16877431 - 09/19/12 11:40 PM (8 months, 24 days ago) |
|
|
Quote:
Humility said:
Don't forget cannabis lowers your IQ and is carcinogenic and is highly dangerous.
Fucking lying pieces of shit.
dont forget it is also a leading cause of testicular cancer.
--------------------
Think for yourself, question authority
|
psyconaught
Chemical Connoisseur
Registered: 11/04/10
Posts: 2,244
Loc: southern oregon
Last seen: 3 minutes, 34 seconds
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: psyconaught]
#16877435 - 09/19/12 11:41 PM (8 months, 24 days ago) |
|
|
i also remember reading in my health book back in high school that its supposed to lower testosterone levels in men, yet raise them in women 
--------------------
Think for yourself, question authority
|
physicist
Registered: 01/11/11
Posts: 2,073
Loc: County Line Road
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: psyconaught]
#16877745 - 09/20/12 12:38 AM (8 months, 24 days ago) |
|
|
|
grump
Stranger
Registered: 10/28/09
Posts: 24
Last seen: 2 months, 2 days
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: physicist]
#16878073 - 09/20/12 01:55 AM (8 months, 24 days ago) |
|
|
They don't synthesize to make it better either, they do that to make it unnatural so that they can cash in. Synthesizing will probably bring fucked up side effects the natural version doesn't. Sad
|
mr.niceguy
Newb on a Mission
Registered: 07/25/12
Posts: 108
Loc: Da Dirty South
Last seen: 5 months, 17 days
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: grump]
#16878363 - 09/20/12 03:14 AM (8 months, 24 days ago) |
|
|
"We used injections in the animal testing and are also testing pills," he said. "But you could never get enough Cannabidiol for it to be effective just from smoking."
I take this as a challenge
--------------------
 "IN THIS BRIGHT FUTURE, YOU CAN'T FORGET YOUR PAST"
|
Alan Rockefeller
Mycologist
Registered: 03/10/07
Posts: 31,943
Last seen: 21 hours, 39 minutes
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: grump]
#16879033 - 09/20/12 10:48 AM (8 months, 24 days ago) |
|
|
Quote:
Gilgamesh18 said:
Il bet these scientists will suffer some unfortunate accidents in the weeks to come.
I doubt it. No other marijuana researchers have suffered unfortunate accidents at suspicious times.
Quote:
grump said:
They don't synthesize to make it better either, they do that to make it unnatural so that they can cash in.
And also so they don't need to deal with getting approval for marijuana.
Quote:
Synthesizing will probably bring fucked up side effects the natural version doesn't. Sad
Probably not, they are unlikely to change the molecule very much.
|
badchad
Mad Scientist
Registered: 03/02/05
Posts: 9,217
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: Alan Rockefeller]
#16879114 - 09/20/12 11:12 AM (8 months, 24 days ago) |
|
|
It's not exceptionally hard to get approval to do this type of research with THC and other schedule 1 substances. It's the human stuff that's difficult.
But there are always problems when "jumping" to humans. Lots of things kill cancer in vitro.
--------------------
...the whole experience is (and is as) a profound piece of knowledge. It is an indellible experience; it is forever known. I have known myself in a way I doubt I would have ever occurred except as it did.
Smith, P. Bull. Menninger Clinic (1959) 23:20-27; p. 27.
...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.
Osmond, H. Annals, NY Acad Science (1957) 66:418-434; p.436
|
RonaldFuckingPaul
Our Dear Leader
Registered: 10/31/07
Posts: 13,464
Loc: Straight Outta Compton
Last seen: 4 hours, 34 minutes
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: badchad]
#16879209 - 09/20/12 11:44 AM (8 months, 24 days ago) |
|
|
I was about to post this article. Cannabidiol is a very useful molecule. I wish it didn't take 10 years to get a fucking drug approved by the FDA.
|
Gilgamesh18
Registered: 03/01/12
Posts: 3,836
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: Alan Rockefeller]
#16879663 - 09/20/12 01:46 PM (8 months, 24 days ago) |
|
|
Quote:
Alan Rockefeller said:
Quote:
Gilgamesh18 said:
Il bet these scientists will suffer some unfortunate accidents in the weeks to come.
I doubt it. No other marijuana researchers have suffered unfortunate accidents at suspicious times.
Quote:
grump said:
They don't synthesize to make it better either, they do that to make it unnatural so that they can cash in.
And also so they don't need to deal with getting approval for marijuana.
Quote:
Synthesizing will probably bring fucked up side effects the natural version doesn't. Sad
Probably not, they are unlikely to change the molecule very much.
Illuminati
--------------------
|
46 and 2
Zen Masta
Registered: 03/02/12
Posts: 255
Loc: Texas
Last seen: 1 month, 17 days
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: RonaldFuckingPaul]
#16879910 - 09/20/12 02:37 PM (8 months, 24 days ago) |
|
|
Ron,
I like your howl's moving castle gif. It was a really awesome flick!
Aside from that, Rick Simpson has been saying this stuff for years. Additionally, a university in Spain also discovered marijuana's tendency to promote apoptosis in cancerous cells back in the 1990's. The knowledge has always been there, but so has the blatant neglect of the world's governments.
--------------------
Even if it seems certain that you will lose, retaliate. Neither wisdom or technique has a place in this. A real man does not think of victory or defeat. He plunges recklessly towards an irrational death. By doing this, you will awaken from your dreams. - Tsunetomo Yamamoto
|
46 and 2
Zen Masta
Registered: 03/02/12
Posts: 255
Loc: Texas
Last seen: 1 month, 17 days
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: Gilgamesh18]
#16879929 - 09/20/12 02:39 PM (8 months, 24 days ago) |
|
|
Quote:
Gilgamesh18 said:
Quote:
Alan Rockefeller said:
Quote:
Gilgamesh18 said:
Il bet these scientists will suffer some unfortunate accidents in the weeks to come.
I doubt it. No other marijuana researchers have suffered unfortunate accidents at suspicious times.
Quote:
grump said:
They don't synthesize to make it better either, they do that to make it unnatural so that they can cash in.
And also so they don't need to deal with getting approval for marijuana.
Quote:
Synthesizing will probably bring fucked up side effects the natural version doesn't. Sad
Probably not, they are unlikely to change the molecule very much.
Illuminati
did the last name "Rockefeller" give it away... ?
--------------------
Even if it seems certain that you will lose, retaliate. Neither wisdom or technique has a place in this. A real man does not think of victory or defeat. He plunges recklessly towards an irrational death. By doing this, you will awaken from your dreams. - Tsunetomo Yamamoto
|
ragefanjr
Cookies4Rookies
Registered: 04/05/08
Posts: 95
Loc: Valparaiso, Ind.
Last seen: 7 months, 6 days
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: wre]
#16880772 - 09/20/12 05:06 PM (8 months, 23 days ago) |
|
|
It's too bad the federal government will pay off junk science "experts" to keep the lies flying higher than cannabis would ever make anyone. Sad times.
--------------------
Cooooooookies! Chomp Chomp Chewey Chomp!!!
This program has been brought to you by dirt. Dirt...it's been around so long it's considered to be older than...wait a minute...
|
grump
Stranger
Registered: 10/28/09
Posts: 24
Last seen: 2 months, 2 days
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: 46 and 2]
#16881975 - 09/20/12 08:29 PM (8 months, 23 days ago) |
|
|
"And also they don't need to deal with getting approval for marijuana"
Is it's anything like opiate based drugs, they'll have half the country hooked in no time
"Probably not, they are unlikely to change the molecule very much"
Nearly every prescription drug is a synthesized form of a natural molecule. We've all heard the ridiculous lists of side effects alot of prescription drugs have. I'd love to see an example of a synthesized form having as few side effects as the natural. Even synthesized vitamins that haven't been changed "very much" cause all sorts of problems the natural form does not. Folic acid has been shown to cause cancer, folate has not, one of thousands of examples. In fact nearly every prescription drug ever could be put beside it's natural form and used as an example
|
badchad
Mad Scientist
Registered: 03/02/05
Posts: 9,217
|
Re: Marijuana And Cancer: Scientists Find Cannabis Compound Stops Metastasis In Aggressive Cancers [Re: grump]
#16882103 - 09/20/12 08:50 PM (8 months, 23 days ago) |
|
|
Quote:
grump said:
Nearly every prescription drug is a synthesized form of a natural molecule. We've all heard the ridiculous lists of side effects alot of prescription drugs have. I'd love to see an example of a synthesized form having as few side effects as the natural. Even synthesized vitamins that haven't been changed "very much" cause all sorts of problems the natural form does not. Folic acid has been shown to cause cancer, folate has not, one of thousands of examples. In fact nearly every prescription drug ever could be put beside it's natural form and used as an example
This has a lot to do with how adverse events are coded.
If someone in a clinical trial feels funny, it's coded as "feeling abnormal". If you get a slightly upset stomach, "nausea" is added to the list.
If you coded MJ the same way, the side effects would appear just as bad: "anxiety", "feeling abnormal", "dysphoria", "euphoria", etc. etc.
--------------------
...the whole experience is (and is as) a profound piece of knowledge. It is an indellible experience; it is forever known. I have known myself in a way I doubt I would have ever occurred except as it did.
Smith, P. Bull. Menninger Clinic (1959) 23:20-27; p. 27.
...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.
Osmond, H. Annals, NY Acad Science (1957) 66:418-434; p.436
|
|
Images only 
Threaded
Previous
Index
Next
Shop for: 
Edit 
Reply 
