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OfflineWiccan_SeekerA
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Samuel L Jackson]
    #15666560 - 01/14/12 08:32 PM (1 year, 4 months ago)

I don't think Salvia should be smoked. I agree with you its a big blow to the heart. also the circulatory system, its one cloud of confusion and before you can do anything productive with it its gone.

Quidding small amounts is a completely different experience.


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OfflineRexter
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15666627 - 01/14/12 08:47 PM (1 year, 4 months ago)

Hey Wiccan if I quid a small amour of 75x is is like a pinch? Is there a link explaining it I know you can't help with dosage. But it would be of great help

I mean like is it not so intense on the body ?


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Fuck any drug that dosnt have a vowel -me


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Meteloides said:
Stick to naturally occurring substances! Like Shrooms! And DMT! And Datura! And Amanita Phalloides! And Nutmeg! And Hemlock!
That'll expand the shit out of your DNA.
:ancientaliens:


Edited by Rexter (01/14/12 08:53 PM)


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Offlinelifeiswhatyoumake
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15666640 - 01/14/12 08:52 PM (1 year, 4 months ago)

I love Salvia.  Most people don't know how to enjoy it.  I do :smile:


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OfflineWiccan_SeekerA
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Rexter]
    #15666643 - 01/14/12 08:53 PM (1 year, 4 months ago)

What I do is constantly chew leaves for 10 minutes before swallowing. A few leaves can do the trick for me 1-2 leaves (about 0.1-0.2gr) is enough for treshold effects but can send you on a substantial trip in the aftermath of MDMA or work as a nod enhancer on poppy tea.

I dont believe your Salvia 75x is really 75x stronger than salvia leaf. Salvinorin is 0.3% of the untreated leaf.

But if it is 75x stronger, you're really talking a few miligrams.

Dont waste extract on chewing, get leaf for cheap.


Edited by Wiccan_Seeker (01/14/12 08:53 PM)


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Onlinepyrate999
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15666702 - 01/14/12 09:11 PM (1 year, 4 months ago)

2-MeO-Ketamine? :strokebeard:

Salvinorins


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OfflineMorphogenesis
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15667982 - 01/15/12 03:19 AM (1 year, 4 months ago)

Quote:

Wiccan_Seeker said:
I don't think Salvia should be smoked.




Speak for yourself.

I'm sure there are those who believe DMT shouldn't be smoked either.

You can ride a bicycle to New York city or you can take a flight.

Guess which one I'm on?


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OfflineMorphogenesis
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Beanhead]
    #15668018 - 01/15/12 03:29 AM (1 year, 4 months ago)

Quote:

Beanhead said:

Do you have more information about this WONDERFUL new RC that is coming? Oh boy I want to try this one

I do want to refer you to some information regarding 4-methylaminorex, stating that the rc won't be neurotoxic is a bit unbelievable.





No one in this thread said anything about any RC being wonderful. Skip the hyperbole.

Regarding 4-EAR, you can find research from all sides of the issue, as always.

Here are studies suggesting the 4 methylated aminorex likely isn't neurotoxic. (Personally, I don't much give a shit about tweaker drugs).

"There have been three studies studying possible neurotoxicity of 4-methylaminorex. First study[13] using quite high doses (highest dose caused clonic seizures and some rats died) in rats and studying short term effects (rats were killed 30 min to 18 h after injection of 5, 10 or 20 mg/kg of racemic cis-4-methylaminorex) suggested reduction in tryptophan hydroxylase (TPH) activity (a possible marker for serotonin neurotoxicity) but citing study: "No change in TPH activity was observed 30 min after injection; by 8 h the activity of this enzyme appeared to be recovering." and "this agent is significantly less neurotoxic than methamphetamine or MDMA."

Study[14] published 2 years later than first one also suggested reduction in tryptophan hydroxylase activity, they used quite high dose too (10 mg/kg of cis-4-methylaminorex) and studied also long term effects (rats were killed 3 h, 18 h or 7 days after injection), they found reduction of 20-40% of tryptophan hydroxylase (TPH) activity and "recovery of TPH activity occurred 18 h after treatment, but was significantly decreased again by 7 days." but "It is noteworthy that, unlike the other analogs, the striatal levels of 5-HT did not decline with TPH activity following multiple 4-methylaminorex treatment"

Latest study[15] (using mice) was not able to find any long term effects suggesting neurotoxicity and they found instead increase in serotonin levels, they used quite high doses too(15 mg/kg of each isomers studied) "The dosages used in the present experiments are about 6-10 times than the effective doses of aminorex and stereoisomers inhibition of food intake." Doses were repeated 3 times a day and mice were killed 7 days after last dose. "Since a long-lasting depletion of dopamine or 5-HT appears to be a good predictor of dopamine or 5-HT neurotoxicity (Wagner et al. 1980; Ricaurte et al. 1985), the results suggest that the aminorex compounds except 4S,SS-dimethylaminorex, unlike MDMA or fenfluramine, are not toxic to either dopamine or 5-HT neurotransmitter systems in CBA[disambiguation needed ] mice. It was reported that although multiple doses of 4-methylaminorex caused long-term (7 days) declines in striatal tryptophan hydroxylase activity in SD rats, no changes were found in 5-HT and 5-HIAA levels (Hanson et al. 1992).[12]

That first study [11] also suggested reduced dopamine (DA) levels (a possible marker for dopamine neurotoxicity), but citing study: "However, 8 h after drug administration no differences from control values were seen in DA, DOPAC or HVA levels." and again later studies [12-13] didn't find any long term reduction."


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OfflineWiccan_SeekerA
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Morphogenesis]
    #15668322 - 01/15/12 07:38 AM (1 year, 4 months ago)

Quote:

Speak for yourself.

I'm sure there are those who believe DMT shouldn't be smoked either.





DMT is accepted by the psychedelics community, salvia almost universally rejected because of the abrasive unhelpful nature of many smoked Salvia experiences. You dont get time to adjust to it, well most of us.


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OfflineRexter
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15668334 - 01/15/12 07:45 AM (1 year, 4 months ago)

Hey are there actually physical side effects that are dangrous from salvia?  Cuz I have all this 75x so...


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Fuck any drug that dosnt have a vowel -me


"Ha! Marshall you're so funny man You should be a comedian, god damn!" Unfortunately I am I just hide behind the tears of a clown"


Meteloides said:
Stick to naturally occurring substances! Like Shrooms! And DMT! And Datura! And Amanita Phalloides! And Nutmeg! And Hemlock!
That'll expand the shit out of your DNA.
:ancientaliens:


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OfflineWiccan_SeekerA
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Rexter]
    #15668357 - 01/15/12 07:57 AM (1 year, 4 months ago)

Yes. Shortly after you toke your blood pressure surges (systolic like 160 or 180) and the heart races. Smoking salvia is a sudden blow to the cardiovascular system and you';ree completely out of it while it happens so you might combine serious cardiovascular effects with that amounts to streneous exercise.


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OfflineRexter
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15668364 - 01/15/12 08:00 AM (1 year, 4 months ago)

.... Why would you tell me that :kingcrankey:


--------------------
Fuck any drug that dosnt have a vowel -me


"Ha! Marshall you're so funny man You should be a comedian, god damn!" Unfortunately I am I just hide behind the tears of a clown"


Meteloides said:
Stick to naturally occurring substances! Like Shrooms! And DMT! And Datura! And Amanita Phalloides! And Nutmeg! And Hemlock!
That'll expand the shit out of your DNA.
:ancientaliens:


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OfflineWiccan_SeekerA
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Rexter]
    #15668369 - 01/15/12 08:03 AM (1 year, 4 months ago)

Because you asked, and I don't believ e in lying or sugarcoating.


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InvisibleIrishdrunk
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15668371 - 01/15/12 08:04 AM (1 year, 4 months ago)

Is there any research chems I can order which are similar to phencyclidine?

:strokebeard:


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InvisibleSamuel L Jackson
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15668374 - 01/15/12 08:05 AM (1 year, 4 months ago)

Quote:

Wiccan_Seeker said:
you';ree completely out of it while it happens so you might combine serious cardiovascular effects with that amounts to streneous exercise.




:lolsy:

the first time i smoked salvia i thought it didnt work because i felt nothing for 30 seconds and then all of a sudden it slapped me in the face with such intensity that i jumped out of my seat.

i didnt move after that though. i was too busy looking around trying to figure out what was happening.


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InvisibleIrishdrunk
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Samuel L Jackson]
    #15668380 - 01/15/12 08:07 AM (1 year, 4 months ago)

lol thats awesome.....first time I tried it I held it in and that's the last thing I remember before waking up covered in sweat and my friends were laughing their asses off.:crankey:


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OfflineWiccan_SeekerA
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Irishdrunk]
    #15668386 - 01/15/12 08:11 AM (1 year, 4 months ago)

hmmm, closer than MXE? 3-MeO-PCP perhaps. Much stronger in dose and effects than MXE.


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InvisibleIrishdrunk
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15668387 - 01/15/12 08:11 AM (1 year, 4 months ago)

Nice!:awehigh:


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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Irishdrunk]
    #15668389 - 01/15/12 08:13 AM (1 year, 4 months ago)

At first 3-MeO-PCP is not unlike MXE but then, above 15-25mg, depending on the individual, it gets UNBELIEVABLY intense.


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InvisibleIrishdrunk
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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Wiccan_Seeker]
    #15668391 - 01/15/12 08:16 AM (1 year, 4 months ago)

I have too much anxiety to do high doses of anything.  I can't even smoke weed without getting paranoid lol, I'd have to try a small amount of that stuff for sure.

Unless I take a few klonoz or Vals first.


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Re: 2-MeO-Ketamine - Coming Soon to a Theater Near You [Re: Irishdrunk]
    #15668402 - 01/15/12 08:22 AM (1 year, 4 months ago)

The highest doses I can take are MDMA and Methoxetamine. Methoxetamine of those definitely takes me highest.


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Amazon Shop for: Salvia

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