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Macromerine is a psychoactive phenethylamine found in some cacti, & is a close analogue to mescaline. From what I've read, the amounts of Macromerine found in psychoactive cacti is rather minute, so it's possible extraction would have to be done to reap most of it's effects.
I've never had any expierence with it, but I'm always researching & finding out more about natural psychedelics & dissociatives that differ from the typical Serotonergics (i.e. Mescaline, pscilocybin, DMT, LSD, ect).
Anyone here ever take any of the cacti it's found in, or make an extract of it? If so, how was it? I have my doubts as this one is rather obscure, but I'm quite interested.