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 bourndead
Down to Earth by Default
Registered: 07/06/10
Posts: 1,029
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 Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: jivJaN]
#13179344 - 09/11/10 09:11 AM (1 year, 8 months ago) |
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Quote:
jivJaN said:
i wanna know why people see eyes , and why i see them eeeevery time i eat the mushroom 
I used to see faces in everything on LSD and Psilocybin, and after my first few trips I'd still see them in many things...sober.
I remember reading that people see things like faces and eyes because it's just an associative/familiarity thing...we're seeing them all the time in our daily lives and they just bleed into other things after awhile.
I used to swear I saw faces, some tortured, some happy, in wood, trees etc. Was on a trip thinking that it was the souls of the dead which had been returned to the earth and reborn into trees.
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"I don't have a God complex, you've got a simple God"
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SuperD
Lophophiend
Registered: 10/05/03
Posts: 5,188
Loc: My stash box
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: bourndead]
#13180338 - 09/11/10 01:03 PM (1 year, 8 months ago) |
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My field of vision has been covered entirely by intricate geometric shapes before, but I don't recall ever seeing faces of any type on any of my trips.
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I'd like you to meet my local drug dealer 
Bruce Campbell for a day! said: Go misidentify a mushroom please.
I'm a psilovibin' psilocybeing 
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nasem
Stranger
Registered: 12/19/09
Posts: 338
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: SuperD]
#13181144 - 09/11/10 04:41 PM (1 year, 8 months ago) |
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I saw my grandfather's corpse floating above me in the dark. That scared me shitless
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I dont know
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 Psilly Rabbit
Graduate Researcher
Registered: 09/17/08
Posts: 382
Loc: 127.0.0.1 
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: nasem]
#13184518 - 09/12/10 12:25 PM (1 year, 8 months ago) |
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Apologies for not posting sooner, I have been so busy. I just wanted to say that this is a great move forward for science.
This study has the potential to re-awaken a an area of science that stigma and mis-information had almost eradicated. It is
great to see individuals in the professional community and in the media embracing these studies in a new light without all the
stigma associated with the use of and I quote, "Illegal" substances. Perhaps one day they could do a study of N,N-Dimethyltryptamine
in terminal patients.
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"But first the notion that man has a body distinct from his soul is to be expunged; this I shall do, by printing in the infernal method, by corrosives, which in Hell are salutary and medicinal, melting apparent surfaces away, and displaying the infinite which was hid. If the doors of perception were cleansed every thing would appear to man as it is, infinite. For man has closed himself up, till he sees all things thro' narrow chinks of his cavern."
-William Blake
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idunno
PinkWebBuffalo
Registered: 03/02/10
Posts: 1,087
Last seen: 9 months, 30 days
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: Psilly Rabbit]
#13184579 - 09/12/10 12:36 PM (1 year, 8 months ago) |
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The same chemical- synthetic or natural could be totally different, There are many analogs, mirror reverse molecules etc, in laymans terms-
Like the difference between, sativa and indica or Pans and cubes- same stuff different effects. Edit: just like the different types of Dmt isomers, Cocaine isomers etc ie, hydrocloride ,bromide and other bases etc. BUT IN SHORT YEA FOR THE STUDY
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The death of one man is a tragedy. The death of millions is a statistic.. Josef Stalin
Edited by idunno (09/12/10 12:39 PM)
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MushroomTrip
Dr. Teasy Thighs
 
Registered: 12/02/05
Posts: 13,719
Loc: red panda village
Last seen: 1 day, 19 hours
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: idunno]
#13184600 - 09/12/10 12:41 PM (1 year, 8 months ago) |
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The difference between sativa and indica comes from the varying quantities of alkaloids in them, and the concentration of THC.
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All this time I've loved you
And never known your face
All this time I've missed you
And searched this human race
Here is true peace
Here my heart knows calm
Safe in your soul
Bathed in your sighs
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AUtrippin
War Eagle
Registered: 07/27/10
Posts: 147
Loc: Auburn, AL
Last seen: 1 year, 7 months
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: MushroomTrip]
#13186801 - 09/12/10 07:28 PM (1 year, 8 months ago) |
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This is great. Isn't John's Hopkins also doing a study?
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Dan4th
Psilocybin Researcher
Registered: 10/22/07
Posts: 31
Loc: San Francisco Bay Area
Last seen: 5 hours, 49 minutes
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: AUtrippin] 1
#13187852 - 09/13/10 12:34 AM (1 year, 8 months ago) |
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The New York Times ran the following announcement this week about findings published in the Archives of General Psychiatry from the Harbor-UCLA Medical Center psilocybin study:
Magic Mushrooms’ May Help Cancer Patients, Study Says
By REUTERS
Published: September 6, 2010
The hallucinogen psilocybin, known by the street name magic mushrooms, may help ease the anxiety that often accompanies late-stage cancer, researchers said Monday. Cancer patients given a moderate dose of psilocybin, whose effects are similar to those of LSD, were measurably less depressed six months after a single dose compared with a placebo, researchers reported in the Archives of General Psychiatry. The pilot study of 12 patients was devised to prove that hallucinogenic drugs could be studied safely as a way to relieve the distress of advanced cancer. It revives a field of study from the 1950s to the early 1970s that suggested some patients experienced powerful and sustained improvement in mood and anxiety from hallucinogens. The studies were abandoned in the early 1970s when drugs like LSD became used on the streets, leading to strict federal laws regulating them.
A version of this brief appeared in print on September 7, 2010, on page A15 of the New York edition.
What's important to remember is that this study is treating anxiety and NOT cancer.If you are curious about similar studies that are currently active, here's a link to info on a study at the Johns Hopkins School of Medicine: http://www.cancer-insight.org For additional information about FDA-approved, registered studies, try www.clinicaltrials.gov (search for key word "psilocybin")
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Dan4th
Psilocybin Researcher
Registered: 10/22/07
Posts: 31
Loc: San Francisco Bay Area
Last seen: 5 hours, 49 minutes
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: AUtrippin] 1
#13187855 - 09/13/10 12:35 AM (1 year, 8 months ago) |
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Yep. Johns Hopkins is recruiting: : http://www.cancer-insight.org
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FleshCap
Sergeant Spore
Registered: 11/10/08
Posts: 581
Loc: Los Angeles Underground
Last seen: 7 months, 5 days
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: Dan4th]
#13190780 - 09/13/10 05:11 PM (1 year, 8 months ago) |
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The article indicated that the purpowof the study was to determine if mushrooms were safe or not... I think the researchers knew the answer already. This study is part of an ongoing effort to make psychedelics more accepted in the scientific community.
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I'll mail you FREE Mushroom Stickers & Zip Bags, Click Here.
Click here to visit the SACRED MUSHROOM ART GALLERY.
"I am a neo-tribal cyberpunk from the 6thdimension and the Mushroom is my spiritual Ally.
Now excuse me, you're blocking the entrance to the portal."
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Synesthetic
Ratings go in journal.
Registered: 12/11/08
Posts: 2,715
Loc: Tooele, UT
Last seen: 1 year, 16 days
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: FleshCap]
#13196752 - 09/14/10 08:19 PM (1 year, 8 months ago) |
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Just to clear a few things up...
Psilocybin, I'm pretty sure, isn't synthesized but extracted from P. cubensis.
And heroin isn't natural, but not fully synthetic, either. Acetic Anhydride + Morphine (which is natural) = diacetyl morphine (heroin).
The isolated psychoactives don't work the same as when taken in their natural forms because the natural forms have other alkaloids and other chemicals that affect the brain and body in different ways.
That's why THC alone causes high anxiety and other horrible things but THC + the other cannabinoids produce all of those wonderful effects everyone loves.
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curenado
73rd Man
Registered: 04/01/03
Posts: 2,601
Loc: North Central Arkansas
Last seen: 1 year, 3 months
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: Synesthetic]
#13196914 - 09/14/10 08:52 PM (1 year, 8 months ago) |
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<<Psilocybin, I'm pretty sure, isn't synthesized but extracted from P. cubensis.>>
Hofman synthesized it, and I don't know what form they are using with certainty but I believe it is the synthetic. One of them will be back soon to say...
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Yours in the Natural State!
"The woods are lovely, dark and deep; but I have patches to keep, and jars to sterilize before I sleep...."
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Synesthetic
Ratings go in journal.
Registered: 12/11/08
Posts: 2,715
Loc: Tooele, UT
Last seen: 1 year, 16 days
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: curenado]
#13198006 - 09/15/10 05:45 AM (1 year, 8 months ago) |
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Even so, there are only a few cases where a chemical compound can have the same atomic makeup but a different structure, which causes it to act differently.
If Hoffman was trying to truly synthesize psilocybin, he'd know not to accidentally make it the way it isn't in nature because doing so can have very unpredictable results.
For example...Water is usually arranged HOH, but if you add some DC you can force the molecules to go OHH, which is a gas called Brown's Gas and burns extremely hot and explosively.
Another example is a morning sickness drug that was experimented with sometime in the 50s or 70s (my history sucks I'm sorry). One version of the drug is very effective and harmless to the child, but the mirror image (chiral) version of the drug will still control the sickness at the cost of interfering so much with the fetus that it's born with horrific birth defects.
Chemists, especially those involved in pharmacology, know better than to screw around like that. If it's called psilocybin, it's the same psilocybin that's in mushrooms on a molecular level
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curenado
73rd Man
Registered: 04/01/03
Posts: 2,601
Loc: North Central Arkansas
Last seen: 1 year, 3 months
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: Synesthetic]
#13199327 - 09/15/10 12:02 PM (1 year, 8 months ago) |
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Oh yeah - I was not disagreeing with you by any means. In fact you are so right that medically, we just have to identify those features and responses and factor them in and it isn't impossible but it does require more effort.
The pills Hofman synthesized were at first rejected by Maria Sabina because their onset was slower. Later, she said the pills would let her do vigils even when the mushrooms were not in season.
So, the synthetic must be somewhat effective at least in the non-physical areas.
What I would like to know (if we ever get done holding stuffed animals and talking about our feelings) is simple; does the synthetic exhibit the same effectiveness in intractable infection, tumors and pain that the real deal does. If it does, is it equal or better?
Because not everyone tolerates psilocybin in adequate therapeutic doses for some things, but they might be able to tolerate the pill, especially if we "turn down" the side effects part.
I have gotten less "Grrr!" about the psychologists (not much though..) but still, the real purpose of psilocybes is for healing sickness. The rest is side effects and you can grin all day long and not change my mind about that. Everything else is getting way into the risk zone and ripe for rampant abuse.
Like one Shroomerite said "Way too much power" for people to be using on people after such a fashion.
But anyway - you have a disease that will kill you if not gotten rid of so what do you pick?
This:
(under construction - Wrong Psychologist )
(Dr. Roland Griffiths, not pictured here, Studies the occasion of mystical-type experiences having substantial and sustained personal meaning and spiritual significance) Though I think he accepts believers only for his data, whereas I would throw them all in a fish tank and count the ones who said "I saw Jesus!" as opposed to the ones who just giggled and saw the pretty colors (about 1 out of three I believe - untested) Also, I would never allow the risky "God in a pill!" thing to be attached to me because that to me would be bogus. We do not know the whole of why these things happen and should not try to create the illusion of it. I also think it's funny to give people a psychotomimetic and then say it was more than their own self and reflections. God is not in the pill anymore than in every leaf or bit of salt. That is bad psychiatry.
This!
(PICTURE REMOVED because Dan4th claims it is different than it looks or has been in the press for the public - see later posts. But this using them on terminals is about as open as the "Food Safety Bill" so until that changes....I'm still me.)
This is the guy that I don't want getting ahold of one of my patients with his "Here, eat this mushroom and you won't worry so much about being terminal!" ("Dr. Euthanasia Parlor")
When the answer is:
"Here, a lot of people have fun giggling with their friends on this mushroom which is also going to help get rid of your terminal thing there. Don't eat just once! Oh, and by the way, no matter what hype you may have read, not everyone is obligated to imaginary guide their trip on any spiritual thing and that is really not my business. Some people just have a good time and enjoy the pretty colors. It's a side effect. If something neat does happen, that's you and God's personal business as well."
or This:
Savage/Physician - Cancer-stomp-the-shit-out-of-er
Because the former serves God and Country by making you feel better about dying, but the plain one that knows ya says "How 'bout fuck the fairy tales and Stanislov Groff and lets just not die? MMk? How 'bout that?"
I guess it just looks too much like "Get 'em high and let 'em die" to me, and my patients would be like "Fuck that! Get me high to fix me if you will, but get 'er done!"
But - I have decided to be less vehement in my disdain of psychological applications. (WHAT?!) Yes, and why? Because I HATE the drugs they kill them with in hospice. I would rather see someone already in hospice and "committed" to die have that type of care than "mellaril" and some of the other atrocious stuff I see. Yes, I would rather, if I am going to lose one for sure, see them with Dr. Grinny Pants (not that sinister Grob, someone like Griffiths) eating psilocybin than being grotesquely medically euthanized and laying there in "mellaril misery" unable to complain or ask for help.
I lost one not long ago, and those hospice vultures started circling (they keep pretty clear of me though - heh) and what did they bring? Mellaril! Sure, my patient looked "quiet" to his family, but what was going on inside still makes me sick to contemplate.
Plus, "Johnny TouchFaith" died in his hammock at home of pancreatic cancer, drifting away with Maria Sabina instead of poisoned with FUCKING MELLARIL!
...and that broke my heart. Made me look at this use in a different way, as long as it is ONLY for those committed to dying - everybody else needs to forget fairy tales and psychology and get fucking better, if they are a clever cabbage.
and yes, if someone said "I am going to get better and I am taking care of it, I would just like to break up this head a little. I promise no one will tell me how "ok it is to die" if I go do their thing." I would approve of that too.
Generally, for health, some giggles and a little shock - you don't need a prescription for that and you know, until somebody breaks the fifty year old retarded paradigm on the hill, psilocybe nor anything else will ever be there because "It makes us happy and content". Somehow, that concept just offends the hell out of hypocrite legislators.
Edited by curenado (09/20/10 10:27 PM)
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BlueDruid
Stranger
Registered: 06/27/06
Posts: 807
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: Synesthetic]
#13199572 - 09/15/10 01:10 PM (1 year, 8 months ago) |
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Quote:
Synesthetic said:
Another example is a morning sickness drug that was experimented with sometime in the 50s or 70s (my history sucks I'm sorry). One version of the drug is very effective and harmless to the child, but the mirror image (chiral) version of the drug will still control the sickness at the cost of interfering so much with the fetus that it's born with horrific birth defects.
You're thinking of Thalidomide, used commercially in the '50's & withdrawn in the early '60's
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sunshine
Pooh-Bah
Registered: 04/03/04
Posts: 23,114
Loc: Upstate penitentiary
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: bourndead]
#13199905 - 09/15/10 02:15 PM (1 year, 8 months ago) |
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What they really need, I presume, is a drug that makes you fearless! They could inject it all the time until you died. That's DEA style.
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ehtdaedlufetarg
Toadstool Taxonomy
Registered: 04/26/07
Posts: 1,864
Loc: Oregon
Last seen: 13 hours, 38 minutes
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: Dan4th]
#13200097 - 09/15/10 02:51 PM (1 year, 8 months ago) |
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Quote:
Dan4th said:
http://news.google.com/news/story?pz=1&cf=all&ned=us&hl=en&topic=m&ncl=dxi7-DbvTaVLqIMmk4vTDoakHkf4M
It's wild how many media sources picked up this story!
Fun Observation. The article towards the bottom of that page on the sie "myfoxorlando.com" Uses a picture of P. mexicana in the article. I knew i recognized the picture from this site, and sure enough it was taken by Cactu.
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curenado
73rd Man
Registered: 04/01/03
Posts: 2,601
Loc: North Central Arkansas
Last seen: 1 year, 3 months
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: ehtdaedlufetarg]
#13200489 - 09/15/10 04:27 PM (1 year, 8 months ago) |
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Quote:
ehtdaedlufetarg said:
Quote:
Dan4th said:
http://news.google.com/news/story?pz=1&cf=all&ned=us&hl=en&topic=m&ncl=dxi7-DbvTaVLqIMmk4vTDoakHkf4M
It's wild how many media sources picked up this story!
Fun Observation. The article towards the bottom of that page on the sie "myfoxorlando.com" Uses a picture of P. mexicana in the article. I knew i recognized the picture from this site, and sure enough it was taken by Cactu.
 That is cool!
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Yours in the Natural State!
"The woods are lovely, dark and deep; but I have patches to keep, and jars to sterilize before I sleep...."
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UroboroS
In Study
Registered: 07/08/10
Posts: 37
Loc: Time-Space/Space-Time
Last seen: 9 months, 5 days
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today [Re: curenado]
#13202992 - 09/16/10 06:22 AM (1 year, 8 months ago) |
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I'm all for research in this field.
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Kapitthaka Mudra
Stranger
Registered: 08/18/10
Posts: 13
Last seen: 1 year, 8 months
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Re: Results of Harbor-UCLA Psilocybin Study Published Online in Archives of General Psychiatry Today! [Re: LanLord]
#13204212 - 09/16/10 11:41 AM (1 year, 8 months ago) |
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