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OfflineGulfripper
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Registered: 10/14/09
Posts: 335
Last seen: 2 months, 27 days
Re: Diphenhydramine? [Re: FuckImAwesome]
    #11379734 - 11/03/09 07:11 PM (2 years, 6 months ago)

Stay away from that stuff. Nothing good will come outta it. Dramamine/dryl is the worst stuff in the world and maybe the only other thing worse than that is CCC's or Robo. As with the Datura read some of the trip reports about it at Erowid and decide if you wanna really do it. I tried the shit when I was a young lad one time Dramamine and one time CCC.  MY dramamine trip consisted of seeing the AOL guy crawling over leaves, puking, hiding in a shed cause the cops were chasing me. I heard em call my mom and tell em I was "On Drugs and they were gonna get me" i then busted outta the shed to see no one there then ran home full blast and got lost even though I lived 5 min walk from were i was and puking some more. CCC involved eating 2 packs or 16 of em because my buddie who was experienced ate that many. I should have learned from the Dramamine incident. I then had the worst experience of my life and puked about 5 times all over the schools water fountain and hallway/wall some kind of a pink exorcist like bile. I then of course walked home in delirium and couldn't drink a sip of water or eat anything for about 2 days. The thought of the pink little pill almost makes me wanna die. As for Robo I had a friend who was like you and drank it for 5-6 months straight and praised it had no problems all around good guy. He started kinda losing it and turning odd and having super bad memory problems like forget super important shit. He got super out of it mentally and physically and eventually it got the best of him and he had to get help and eventually was medvac out and I talked to him about three months ago(this ordeal was in 06-07) and he still has problems. Just trying to say be care full man cause some decisions are irreversible.


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OfflineDrScott
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Registered: 09/12/09
Posts: 805
Loc: Summit of Plateau Sigma Flag
Last seen: 1 year, 9 months
Re: Diphenhydramine? [Re: FuckImAwesome]
    #11379763 - 11/03/09 07:14 PM (2 years, 6 months ago)

Does anyone here know the lethal dose for humans on DPH?
I read it kills rats at 500mg's. So I don't know what a humans' medicine to blood ratio is.

  Also, are you positive pot negates DPH effects?
Because the first time I did it I smoked a lot of weed actually, and it felt great...but maybe that is why I can never get the trip to last more than 4hours.
  That is what truly sucks, I could have played around with this new drug for awhile, but the trip seems to die pretty quickly.
  And, the last time I did it, which is today, I filled my sink with tons of puke...but I couldn't see any pills, and it was about an hour since eating them...which means I am in the clear.


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InvisibledeCypher
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Registered: 02/10/08
Posts: 52,515
Re: Diphenhydramine? [Re: DrScott]
    #11379839 - 11/03/09 07:24 PM (2 years, 6 months ago)

Large doses of delta-9THC appear to increase brain levels of acetylcholine, as THC inhibits acetylcholinesterase.  However, anandamides antagonize muscarinic cholinergic receptors, so the increase in acetylcholine would do no good to counteract the effects of the deliriant.  In my experience cannabis synergizes very nicely with DPH and Datura but the combination can increase detrimental cardiovascular effects and paranoia.


--------------------
We are all in the gutter, but some of us are looking at the stars.


Edited by deCypher (11/03/09 07:30 PM)


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Offlinedisconnect
Stranger
Registered: 09/28/09
Posts: 41
Last seen: 2 years, 5 months
Re: Diphenhydramine? [Re: FuckImAwesome]
    #11380181 - 11/03/09 08:21 PM (2 years, 6 months ago)

Sounds like most that have had negative experiences while on dph have really hated it.I was introduced to it by a friend that loved it to pieces, and before looking further into it, I gave it a shot, about 500mg, combined with 5-6 caffeine pills (don't remember exact amount in mg). I wouldn't choose it over most other drugs, but aside from the hangover, I found it alright. To each their own, I guess. I'm sure set and setting affect the experience greatly.

Quote:

deCypher said:
Large doses of delta-9THC appear to increase brain levels of acetylcholine, as THC inhibits acetylcholinesterase.  However, anandamides antagonize muscarinic cholinergic receptors, so the increase in acetylcholine would do no good to counteract the effects of the deliriant.  In my experience cannabis synergizes very nicely with DPH and Datura but the combination can increase detrimental cardiovascular effects and paranoia.




Good to know, thanks!


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