With the legality of salvia heavily threatened in the US and it being banned or considered illegal (in the same class as meth, heroin, cocaine) and so becomes punishable offense to manufacture, use or posses in many other countries. 
I feel its a good idea for people to put some effort into discovering alternatives to salvia that are accessible in countries that have already clamped down their restrictions.

The legality of these possible other plants that contain salvinorin A is a grey area at the moment.  So it could be a good loophole for those in the restricted countries.

I was wondering if anyone out there in the ethnobotanical garden has done any experiments to see which other salvia species have possible activity.
If you don't want to post here then send me a pm.

I have found a few references to possible activity in some but the reports are always anecdotal.

There are well over 700 species .  There must be more than just sally d containing salvinorin A.
Here is a list of some "possibly" active salvias I found of another site.  Anyone have any of these growing.  Especially the ones underlined and bold.
(being a cut and paste I take no responsibility for spelling errors)

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Salvia aegyptiaca: Extracts have antinociceptive effects in animals

Salvia aethiopis: Aethiopinone isolated from roots has antinociceptive effects in animals

Salvia africana-lutea: Water extract has antinociceptive effects in animals

Salvia argentia: Reported to be similar in activity to Salvia splendens

Salvia coccinea: Smoking 1/2 gram of leaves was reported to be "calming"

Salvia divinorum: Active

Salvia Dorrii: Reported to have been smoked by Native Americans and in particular the Ute Tribe for their mildly hallucinogenic effects. Also known as Tobacco Sage.

Salvia dorisiana: Leaves were described as "edible", suggestive oral inactivity.

Salvia elegans:
Reported as orally inactive. Conflicting reports have been made at The ********** forum of oral and smoked activty. There has also been a study done in Chile that reports anxiolytic- and antidepressant-like effects in rats from a hydroalcoholic extract.

i never noticed any effect from smoking it, the smoke does not taste like pineapple nor did the leaves when i ate them. - daylight
Salvia farinacea: Seems active but uninteresting. Smoking it didnt do anything special for me. Just a bit of relaxing activity. - daylight

Salvia greggii: Reported to be active

Salvia guaranitica:
Sedative and hypnotic due to its content of cirsiliol.

Smoking 1/2 dried leaf (leaves are very big) in a bong did not produce significant effects, just a placebo-like relaxation. - unsigned_char72
Salvia haematodes: Sedative, possible antinociceptive effects in animals

Salvia hormium: Leaves and seeds make liquor more inebriating, and powdered leaves make a good snuff

Salvia lavandulaefolie: Extracts inhibit acetylcholinesterase and improve memory and cognition

Salvia leriifolia: Leaf extract sedative, hypnotic, relaxant and antinociceptive in animals

Salvia leucantha:
Smoking the leaves is reported to increase the length of dreams - unsigned_char72

Smoking 200mg of plain leaf didn't seem to have any effect, but I usually don't recall dreams - entheodelic

No effect, but habitual cannabis use rules out dreams for the most part - daylight
Salvia longispicata x farinacea (Mystic Spires): Smoked leaves are reported to be speedy, analgesic and aphrodisiac - zombiesoul

Salvia melissodora: reported to be active

S. mellifera (Black Sage): No effects when smoked as plain leaf - daylight

Salvia mexicana: no effects from quid of 2 leaves.

Salvia miltiorrhiza (dan shen): Roots and leaves are anxiolytic and sedative due to its content of miltirone. Seeds reported to be stimulating.

Salvia nemorosa:
Leaves and especially flowers of the Caradonna and Superba varieties (sometimes reported as its own species) are analgesic and produce vivid dreams when taken orally - zombiesoul

analgesic (but does not alter dreams) when smoked - daylight

The roots are also active - sputnik3

the May Night variety was reported to be weak - ref?

Five grams of superba (19 fresh leaves) or snow hill (33 fresh leaves) variety had no effect when quidded and swallowed. 22 grams (9 spires) of Pink Friesland shredded in hot water, strained and drunk had no effect. - entheodelic

I chewed a quid of one spire and two big leaves (quite a bit of plant matter in my mouth) and felt nothing. Been smoking increasingly larger amounts of flowers with nothing yet - Bum

smoked 1 bowl of just flowers, with a bit of my usual dried greens smoke blend. nothing to note first round. but it wasnt a large amount. didn't weigh it either. - teeko

"Blue Hills": Smoked about .3g dried material, mostly leaves, a few
small flower pieces. Slight heart effects, "rushing" sensation, relaxation and trippy feel, opiate-like euphoria, potentiation of hydrocodone. - ethnophile7

S. nemorosa: 60-80% relief from 500-700mg/day morphine habit - Lemmiwinks

"May Night": Mild - Zombiesoul
Salvia officinalis: Leaves mildly stimulating when eaten or smoked due to their content of thujone. Greatly intensifies/alters the effects of edit.

Salvia sclarea: essential oil is sedative and anticonvulsant

Salvia spathacea:
Gives a high extremely similar to S. nemorosa at 0.3g of plain leaf. Leaves very similar in appearance to nemorosa, they also share a purpling reaction when the leaves are dried out. - daylight

Smoked flowers were awarded the two middle finger (top) award by Zombiesoul

Salvia splendens:
Leaves and flowers reported to be anxiolytic or mild intoxicant when smoked. Although a study by Daniel Siebert seemed to show these effects to be placebo, it seems that some varieties ('Bonfire', 'Blaze of fire') are active and others (the Sizzler series) are not.

Definately active, anxiolytic , sedative, emo-numbing effects from smoking some leaf. Harsh flavor and taste, flowers also active, they burn less but have more unpleasant flavor ~ mutant
Salvia transsylvanica: Reported to have significant analgesic, antipyretic, antiepileptic, antiinflammatory, antiulcerogenic, as well as tranquillizing activities.

Salvia tricolor: Possibly sedative

Salvia virgata: Considered "closely related to S. nemorosa" and possibly the "big leaved" nemorosa that Daylight found similar in effect to S. nemorosas.

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Effects of 1 sublingual leaf of Savlia Splendens
Salvia splendens may be a new psychotropic sage, such as salvia divinorum.

Here is what I have observed with 1 leaf of salvia splendens (in powder) sublingually (leaf material kept under the tongue for 20 minutes):

The first noticeable effect is felt as "heavy eyes". Your eyes seem heavy and, subjectively, globulous.

At the same time you feel a slowing of your thoughts, reminiscent of the effects of SSRIs.

Then you feel a nice feeling of tranquillty and anxiolysis which reminds very much the anxiolysis which can be elicited by MDMA.

This pleasant anxiolysis lasts for a few hours.

Salvia splendens is unknown as a psychotropic agent.


Thursday, 30 October 1997:

Yesterday I observed the following effect with half a leaf of salvia splendens:

Fast anxiolytic effect reminding, again, a component of the anti-stress effect of MDMA and reminding also the long term psychotropic effects which can be induced by captopril together with a SSRI component.

Captopril can induce, after sometimes, at a dose of 50 to 75mg, emotional indifference which, in turn, leaves you unresponsive to normal psychological stress.

So yesterday I was stressed and felt not good,despite the fact I had taken 2mg of a benzodiazepine, lorazepam.

This was due to my wife who often has bouts of depressive ideation with a lot of tears, when approaching menstruations. Seeing her crying I obviously felt anxious and also some autonomic stress effects.

I took half a leaf of salvia splendens sublingually, to see if it could have any effect on this stress and anxiety.

After about 10 minutes my stress and anxiety all of a sudden vanished and I felt perfectly tranquil and "reasonable".

Seeing my wife crying I did not feel anxious or tense anymore but just "rational".

What I noticed was a blunting of emotions, such as seen with captopril for instance, and SSRIs or with MDMA (which, I feel, has a pro-emotional component and an anti-emotional component at the same time).

For about 20 minutes I felt no more anxiety or concern, just rationally quiet, placid!

Then I took another half leaf sublingually and, after a few minutes, I felt sudenly a strange state I perhaps experienced under a high dose of hashish.

My head became light, my body felt numb, and I started to feel, in fact, light everywhere, as if I were suddenly to fly up in the sky like a balloon!

This made me afraid because it felt as if something unknown was on the verge of happening.

To try to combat this feeling I went to the toilet, in order just to "do something". After about 2 minutes this sensation was gone and I again felt the previous effect of salvia splendens.

Conclusion: salvia splendens seems to have a remarkable anxiolytic effect subjectively totally different and distinct from those effects seen with benzodiazepines. It lifts your anxiety without inducing "euphoria" (...which looks exactly like what many pharmaceutical companies are looking for (buspirone...)!!!). On the other hand, you feel emotionally unreactive.

This suggests potential studies concerning the negative symptoms of schizophrenia, if this effect is confirmed by others.

Salvia splendens seems to contain powerful and short-acting active components (salviarin, splendidin? which are clerodane diterpenes) and I guess increasing the dosage might lead to effects partially resembling those of salvia divinorum because this effect of the "unknown" I have felt also with salvia divinorum at 1 leaf dosage sublingually.

Emotional blunting was also very apparent with salvia divinorum, unlike a molecule like gamma-hydroxybutyrate which spectacularly enhances your emotions and sociability.

Claude Rifat

Note: Clerodane diterpenes can be found also in other plants than salvia splendens and divinorum. They might be natural insect repellents used by some salvia species! One at least, from another Labiaceae (Ajuga, a Chinese labiaceae) has hypotensive action. Is there a captoprilic link here?

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UnderNose said:
there are very tight customs regulations here.

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tenacioustornado said:
none are hallicinogens like divinorum that I know of so none will replace it. I've tried nemerosa,coccinea,splendens all to no effect. I've read S. officinalis contains thujone more than wormwood so might be good to combine with cannabis.

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Nice to see some first hand experiance from somebody. But its not good info for me is it.
May I ask what method of injestion and quantity,  this would help me determine if they could be tested further.


One thing I think I might try to aquire is Coleus Amboinicus.
Sorry for the MASSIVE picture.


I must say it looks similar to this, Salvia divinorum


And I found some reports about it on Daniel Siebert's sage wisdom site.

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Wasson also mentioned the curious datum that the Mazatecs regarded Salvia divinorum to be the most important member of a ‘family’ (all, botanically speaking, indeed members of the same family, Labiatae), being la hembra, ‘the female,’ whereas el macho or ‘the male’ was Coleus pumilus Blanco, and el nene, ‘the child,’ or el ajihado, ‘the godson,’ was Coleus blumei Bentham

As for the Coleus species said to belong to the same ‘family’ as Salvia divinorum, Coleus blumei is known to contain terpenoids (García et al. 1973), flavonoids and coumarins (Lamprecht et al. 1975) of unknown psychopharmacology. Terpenoids known as coleones are found in other species of the genus (Arihara et al. 1975), and Coleus blumei was shown not to contain the hypotensive terpenoid colforsin or forskolin (Shah et al. 1980), found in the Ayurvedic medicine gurmal or Coleus barbatus (Andrews) Bentham (Valdés et al. 1987b). Along with Coleus blumei and C. pumilus, the well-known Ayurvedic medicine pashnabhedi, Coleus amboinicus Lourteig (Nadkarni 1976) might be a good candidate for screening for salvinorin A or allied compounds

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Pendell cited the lack of sexes in Salvia divinorum as militating against its identity with pipiltzintzintli, but as he himself allowed, “it is also possible that the reference to gender is metaphorical” (Pendell 1995), as is certainly the case with male/female pairing of entheogenic mushrooms used shamanically in various parts of Mexico (Ott 1993; Rubel & Gettelfinger-Krejci 1976; Wasson & Wasson 1957); likewise with male and female elements of plant combinations in Amazonian ayahuasca potions (Ott 1994). Furthermore, Wasson’s pioneering paper noted exactly this with respect to the leaves of the Shepherdess, said by his Mazatec informants to be ‘the female’ in a ‘family’ including ‘the male,’ Coleus pumilus, and a ‘child,’ C. blumei (Wasson 1962). The lack of botanical sexes in Salvia divinorum constitutes specious grounds to reject the identity of this drug with pipiltzintzintli, given the common use of sex-pairing as a metaphor for entheogenic plant ingestion or dosing

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I take it by this information quoted here that possibly the Mazatec had a type of plant mixture like ayahuasca but containing the so called "family".

Salvia Divonorum being the female.
Coleus Pumilus being the male.
Coleus Blumei being the child.

Or maybe they used them in different situations for different purposes.