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 EFresh
Team Skanc
Registered: 07/21/06
Posts: 6
Last seen: 1 year, 10 months
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 Increasing potency with 5-HTP (trytophan)
#5885621 - 07/21/06 08:09 PM (2 years, 1 month ago) |
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O.k swim just picked up a bottle of the dietary supplement 5-HTP trytophan....he's heard of procedures were adding trytamine to the substrate can increase the amount of psilocybin found in cubensis mushrooms,,,he also knows that trytophan is a well known precurser to tryptamine...he's wondering if adding tryptophan to the substrate would have the same effect as adding tryptamine???
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 RogerRabbit
Bans forPleasure
Registered: 03/26/03
Posts: 16,817
Loc: Pacific Northwest
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 Re: Increasing potency with 5-HTP (trytophan) [Re: EFresh]
#5885636 - 07/21/06 08:15 PM (2 years, 1 month ago) |
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Here we go again. . . .
If you'll scroll down, you'll see this has been covered hundreds of times. Read up on it.
RR
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"I wouldn't want to belong to any club that would have me as a member".
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EFresh
Team Skanc
Registered: 07/21/06
Posts: 6
Last seen: 1 year, 10 months
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Re: Increasing potency with 5-HTP (trytophan) [Re: EFresh]
#5885645 - 07/21/06 08:17 PM (2 years, 1 month ago) |
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Swims also read that mushrooms perform Decarboxylation... now with this trytophan substrate will the mushrooms turn the trytophan into trytamine(wich will make you very sick if you ingest it), turn the trytophan to trytamine then to Psilocybin, or turn the trytophan strait to Psilocybin???
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 fastfred
Registered: 05/17/04
Posts: 4,326
Loc: Dark side of the moon
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Re: Increasing potency with 5-HTP (trytophan) [Re: EFresh]
#5886441 - 07/22/06 01:49 AM (2 years, 1 month ago) |
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You really need to do some reading. There are several threads covering this in the first couple pages in advanced. Look at some of my posts, most of your questions are explained in good detail. Do a search of advanced with "fastfred" in the username box. I think I have around 3-4 threads in the last month or two on this topic.
This diagram might help you...
The simple answer to your question is NO. Tryptophan is highly regulated. You can't increase it much above it's normal level by substrate supplementation. It will probably help to some small extent, but not by much.
-FF
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Acinaxuz
In SomnisVeritas.
Registered: 06/20/06
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Re: Increasing potency with 5-HTP (trytophan) [Re: fastfred]
#5893940 - 07/24/06 10:15 AM (2 years, 1 month ago) |
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Basically EF--You'll receive minimal results, if you receive results at all.
In short, tryptophan doesn't work. Tryptamines have had some results only in HCL form--a watched chemical. TDC (Tryptophan Decarboxylase) is the best route and for the moment generally unattainable.
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All posts are made with only the intent to entertain myself and should ONLY be read with the understanding that they are FICTICIOUS. I do not warrant information I provide for use in illegal activity of any kind nor do I condone it for any reason. Furthermore, I am not, I have never, nor will I in the future, take ANY part in illegal activites.
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Weebl8bob
Lost
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Re: Increasing potency with 5-HTP (trytophan) [Re: Acinaxuz]
#5898804 - 07/25/06 04:36 PM (2 years, 1 month ago) |
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What if one used dried, powdered mushies as your substrate? O.o
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shirley knott
not my real name
Registered: 11/11/02
Posts: 9,000
Loc: London
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Re: Increasing potency with 5-HTP (trytophan) [Re: Weebl8bob]
#5901980 - 07/26/06 01:57 PM (2 years, 1 month ago) |
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are you suggesting the use of final product as raw material for another batch?
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Weebl8bob
Lost
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Re: Increasing potency with 5-HTP (trytophan) [Re: shirley knott]
#5905292 - 07/27/06 01:11 PM (2 years, 1 month ago) |
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Yes.. yes i am O.o
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shirley knott
not my real name
Registered: 11/11/02
Posts: 9,000
Loc: London
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Re: Increasing potency with 5-HTP (trytophan) [Re: Weebl8bob]
#5908953 - 07/28/06 01:26 PM (2 years, 1 month ago) |
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then you are completely nuts!
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hippie_cune
Nowhere Man
Registered: 06/13/06
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Re: Increasing potency with 5-HTP (trytophan) [Re: shirley knott]
#5909031 - 07/28/06 02:07 PM (2 years, 1 month ago) |
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but would it yeild stronger mushrooms?
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shirley knott
not my real name
Registered: 11/11/02
Posts: 9,000
Loc: London
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Re: Increasing potency with 5-HTP (trytophan) [Re: hippie_cune]
#5909155 - 07/28/06 02:48 PM (2 years, 1 month ago) |
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why on earth should it?
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monstermitch
SubstrateEngineer
Registered: 02/10/06
Posts: 3,867
Loc: Arizona Bay
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Re: Increasing potency with 5-HTP (trytophan) [Re: shirley knott]
#5909227 - 07/28/06 03:12 PM (2 years, 1 month ago) |
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fastfred
Registered: 05/17/04
Posts: 4,326
Loc: Dark side of the moon
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Re: Increasing potency with 5-HTP (trytophan) [Re: monstermitch]
#5909471 - 07/28/06 04:20 PM (2 years, 1 month ago) |
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> but would it yeild stronger mushrooms?
Yes. Psilocin is even more easily incorporated into psilocybin than tryptamine.
-FF
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Weebl8bob
Lost
Registered: 06/14/06
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Re: Increasing potency with 5-HTP (trytophan) [Re: fastfred]
#5910449 - 07/28/06 10:44 PM (2 years, 1 month ago) |
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I just figured that the already produced tryptamines would be absorbed by the mycelium and reused as needed or something idunno.. just shooting out ideas lol
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fastfred
Registered: 05/17/04
Posts: 4,326
Loc: Dark side of the moon
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Re: Increasing potency with 5-HTP (trytophan) [Re: Weebl8bob]
#5910788 - 07/29/06 12:27 AM (2 years, 1 month ago) |
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You're right psilocin is well absorbed.
It's pretty foolish to use final product as feedstock for the next round though. It would be interesting to experiment with though, just for the sake of science. Or perhaps if you needed really potent shrooms for some reason. Maybe if there was a "Cubensis cup" or some competition of that nature.
-FF
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cloudtop
Stranger
Registered: 08/16/04
Posts: 66
Loc: bespin
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Re: Increasing potency with 5-HTP (trytophan) [Re: fastfred]
#5911513 - 07/29/06 09:49 AM (2 years, 1 month ago) |
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Or perhaps a psilocybin/psilocin extraction performed on spent substrate/mycelium (though minimal content is available in comparison to the actual mushrooms) and then utilized as an ingredient in future tubs. For people who aren't dealing w/ contams and don't have access to outside gardens, this could be an interesting way of utilizing old substrate.
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peacefromabovecloudtop
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Weebl8bob
Lost
Registered: 06/14/06
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Re: Increasing potency with 5-HTP (trytophan) [Re: cloudtop]
#5913467 - 07/29/06 11:16 PM (2 years, 1 month ago) |
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Hmm.. Im going to give this a go as soon as I get a new set of jars for the winter season :-D
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Frappy
Strange
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Loc: South Florida
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Re: Increasing potency with 5-HTP (trytophan) [Re: cloudtop]
#5920349 - 07/31/06 11:02 PM (2 years, 1 month ago) |
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using mushrooms as substrate for growing mushrooms would be counter productive even if it did work, and even if it made the mushrooms more potent. You'll probably just open yourself up to a greater possibility of contamination issues, but i'm not stopping you from trying. Go ahead and post back with your results.
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toole
white-thumb (Onewhackmycophiliac)
Registered: 05/01/06
Posts: 500
Loc: spore #1203 - bas 2.34 - ...
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Re: Increasing potency with 5-HTP (trytophan) [Re: Frappy]
#5921468 - 08/01/06 10:55 AM (2 years, 1 month ago) |
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You're saying, it would be counter productive...
>'even if it did work' ?
>'even if it made the mushrooms more potent' ?
How is that counter productive...you kinda just threw a double negative out there..
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LynxRufus
Stranger
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Re: Increasing potency with 5-HTP (trytophan) [Re: toole]
#5923167 - 08/01/06 08:56 PM (2 years, 1 month ago) |
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This is all very academic, but the fact that these chemicals readily break down under heat seems to have been missed. You will not succeed pasteurizing old substrates or mushrooms and spawning to them. Both of these will need to be sterilized for any chance of success. In other words, high heat and pressure (which would increase the effects of the heat) would necessarily negate any potential benefits from this idea.
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