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 DNKYD
Turtle!
Registered: 09/23/04
Posts: 12,197
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 High-dose cannabis stimulates growth of brain cells in rats 
#4804732 - 10/14/05 06:25 PM (6 years, 7 months ago) |
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By Jeremy Laurance, Health Editor
Independent Online
Published: 14 October 2005
Cannabis, the third most popular recreational drug after alcohol and tobacco, yesterday won an unlikely accolade from scientists who said that it could boost brain power.
Experiments on rats given a potent cannabinoid have shown the drug stimulates the growth of new brain cells. Canadian researchers found that the drug caused neurons to regenerate in the hippocampus, an area that controls mood and emotions, after one month of treatment.
Its effect was similar to that of the antidepressant drug Prozac, which also stimulates nerve growth in the hippocampus. The rats were less anxious and more willing to eat in a novel environment that would normally make them fearful.
Most drugs, including alcohol, heroin, cocaine and nicotine, have been shown to destroy nerve cells in the hippocampus, the researchers from the University of Saskatchewan, Canada, say. "The present study suggests that cannabinoids are the only illicit drug that can promote adult hippocampal neurogenesis following chronic administration," they write in the Journal of Clinical Investigation.
The finding runs counter to previous research highlighting the risks of cannabis use, including a heightened degree of psychosis in vulnerable users, and an increased risk of lung cancer similar to that in tobacco smokers. The authors say regular cannabis users are known to suffer acute memory impairment, as well as dependency and withdrawal symptoms.
The new research suggests that the size of the dose may be crucial. The results showed that regular injections of high, but not low, doses of the artificial cannabinoid HU210 were associated with anti-anxiety and antidepressive effects.
"These complicated effects of high and low doses of acute and chronic exposure to cannabinoids may explain the seemingly conflicting results observed in clinical studies regarding the effects of cannabinoid on anxiety and depression," the scientists say.
The study emerged from the recent discovery that, unlike other parts of the brain, the hippocampus can generate neurons throughout the lifespan of mammals, including humans.
Natural selection has conserved cannabinoid receptors in animals that have been separated by evolution for 500 million years, suggesting they have an important biological role. Cannabinoids appear to alter the effects of pain, nausea, tumours, sclerosis and other disorders in both animals and humans, the team says.
The experiment involved giving rats regular injections of HU210 for a month. At the end of this time, hungry animals showed significantly less reluctance to eat in a novel environment. Rats are normally neophobic - wary of new situations.
Cannabis, the third most popular recreational drug after alcohol and tobacco, yesterday won an unlikely accolade from scientists who said that it could boost brain power.
Experiments on rats given a potent cannabinoid have shown the drug stimulates the growth of new brain cells. Canadian researchers found that the drug caused neurons to regenerate in the hippocampus, an area that controls mood and emotions, after one month of treatment.
Its effect was similar to that of the antidepressant drug Prozac, which also stimulates nerve growth in the hippocampus. The rats were less anxious and more willing to eat in a novel environment that would normally make them fearful.
Most drugs, including alcohol, heroin, cocaine and nicotine, have been shown to destroy nerve cells in the hippocampus, the researchers from the University of Saskatchewan, Canada, say. "The present study suggests that cannabinoids are the only illicit drug that can promote adult hippocampal neurogenesis following chronic administration," they write in the Journal of Clinical Investigation.
The finding runs counter to previous research highlighting the risks of cannabis use, including a heightened degree of psychosis in vulnerable users, and an increased risk of lung cancer similar to that in tobacco smokers. The authors say regular cannabis users are known to suffer acute memory impairment, as well as dependency and withdrawal symptoms.
The new research suggests that the size of the dose may be crucial. The results showed that regular injections of high, but not low, doses of the artificial cannabinoid HU210 were associated with anti-anxiety and antidepressive effects.
"These complicated effects of high and low doses of acute and chronic exposure to cannabinoids may explain the seemingly conflicting results observed in clinical studies regarding the effects of cannabinoid on anxiety and depression," the scientists say.
The study emerged from the recent discovery that, unlike other parts of the brain, the hippocampus can generate neurons throughout the lifespan of mammals, including humans.
Natural selection has conserved cannabinoid receptors in animals that have been separated by evolution for 500 million years, suggesting they have an important biological role. Cannabinoids appear to alter the effects of pain, nausea, tumours, sclerosis and other disorders in both animals and humans, the team says.
The experiment involved giving rats regular injections of HU210 for a month. At the end of this time, hungry animals showed significantly less reluctance to eat in a novel environment. Rats are normally neophobic - wary of new situations.
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Krishna
कृष्ण,LOL
Registered: 05/08/03
Posts: 23,258
Loc: oakland
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: DNKYD]
#4804920 - 10/14/05 07:21 PM (6 years, 7 months ago) |
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was about to post a link about this as well
here's another article
http://www.medpagetoday.com/Neurology/GeneralNeurology/tb2/1934
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 CptnGarden
fuck this site
Registered: 05/12/04
Posts: 11,945
Last seen: 3 years, 1 month
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: Krishna]
#4805228 - 10/14/05 08:52 PM (6 years, 7 months ago) |
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man with my calculations and high grade cannabis intake, i should be the worlds smartest man in the next 5 years 
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Stonerguy
I smoke penis
Registered: 05/29/04
Posts: 5,538
Loc: Lost
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: CptnGarden]
#4806608 - 10/15/05 06:15 AM (6 years, 7 months ago) |
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Quote:
ShroomieOfDoomie said:
man with my calculations and high grade cannabis intake, i should be the worlds smartest man in the next 5 years
Me too  . If I really want to become smart though I should get to working up to 15 grams a day!!!
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yawn...
SG
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Shdwstr
FSRCanada
Registered: 02/17/01
Posts: 2,156
Loc: Ontario, Canada
Last seen: 1 month, 22 days
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: DNKYD]
#4806700 - 10/15/05 07:35 AM (6 years, 7 months ago) |
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Difinative proof!!!
Rats who do pot get the munchies too! 
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Support the FSRCanada - Donate your prints
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ambros
Stranger
Registered: 09/09/03
Posts: 79
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: Shdwstr]
#4807610 - 10/15/05 12:46 PM (6 years, 7 months ago) |
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Heffy
BrauMeister
Registered: 08/30/04
Posts: 2,399
Loc: International Traveller
Last seen: 6 hours, 52 minutes
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: ambros]
#4882704 - 11/02/05 06:21 AM (6 years, 6 months ago) |
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Someone had a link to the original research of this study. There were like 30 references. Anyone know where it is, I already UTFSE?
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I am the king of Rome, and above grammar! - Emperor Sigismund
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nakors_junk_bag
Lobster Bisque
Registered: 11/23/04
Posts: 2,415
Loc: ethereality
Last seen: 4 years, 1 month
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: Heffy]
#5312713 - 02/18/06 03:08 AM (6 years, 3 months ago) |
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we win again.
It won't be long now and we will find ourselves a home.
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Asshole
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Mitchnast
Trial by Madness
Registered: 10/27/99
Posts: 8,377
Loc: Okanagan 
Last seen: 1 month, 14 days
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: nakors_junk_bag]
#5312862 - 02/18/06 07:05 AM (6 years, 3 months ago) |
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ha ha ha, cool, changes nothing.
Prohibitionists aren't concerned with facts and figures unless it supports their argument.
Furthermore they are politicians. Politics, by design, corrupts reasoning irreparably towards stagnation of process. It is the nature of politicians to take steps backwards to compensate for forward-motions in reality.
This is how status-quo is maintained. Weather or not this is beneficial is moot, those in power ARE in power, so why change things?
Only those WITHOUT power push towards change. and cannot acheive it by design.
Sorry to say this to a culture who thinks its "of peace". but if you want any change, you have to kill a few leaders. As leaders, they should accept sudden death as a function of their position.
Due to establishment of safeguards, it may be nessisary to do irreparable damage to the political infrastructure.
heres a tip to you aspiring terrorists, most of the eastern US power comes from canada.
take out niagra falls power plants and create chaos all through the east US.
It's not SUPPOSED to be one big power grid, but it IS.
the separation between canada and the US is merely an illusion of the establishment. a suggested border re-enforced by a map we saw evry day growing up.
blow up hover dam and take out much of the west.
then sabotage the national guard evry step of the way however possible.
do whatever possible to harm shipping lines.
Use established religous society buildings as disestablishmentarianism fronts and provide shelter and group protection to anyone who needs it in the time of chaos.
this is what it will REALLY take to create an environment where thereas ANY chance of pot EVER becomming a non-crime.
or you can protest peacefully, it keeps you nicely out of the way of the political landscape.
the above is hypothetical of course.
im just saying, pot will always be a big crime, its supporters are right, but powerless against a situation that is wrong, but powerful.
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RemainRandom50
Do You Need ToKnow Me?
Registered: 01/15/06
Posts: 1,695
Last seen: 3 years, 1 month
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: Mitchnast]
#5312931 - 02/18/06 07:56 AM (6 years, 3 months ago) |
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very neat.
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At times I get consumed by my everyday life and will leave the Shroomery. Yet, every time drugs come falling into my life for fun.....I always think about the Shroomery and then I'm back!
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Koala Koolio
TTAGGGTTAGGGTTAGGGTTAGGG
Registered: 01/07/04
Posts: 7,752
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: RemainRandom50]
#5313839 - 02/18/06 03:14 PM (6 years, 3 months ago) |
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"Prohibitionists aren't concerned with facts and figures unless it supports their argument."
To be fair, neither are we for the most part.
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You're not like the others. You like the same things I do. Wax paper, boiled football leather... dog breath. We're not hitch-hiking anymore, we're riding!
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Mitchnast
Trial by Madness
Registered: 10/27/99
Posts: 8,377
Loc: Okanagan
Last seen: 1 month, 14 days
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: Koala Koolio]
#5313859 - 02/18/06 03:22 PM (6 years, 3 months ago) |
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personally im not even interested in arguing.
i want implementation.
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EarthDroid
Old Crank(Veteran)
Registered: 01/25/06
Posts: 409
Last seen: 5 years, 5 months
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: Krishna]
#5317352 - 02/19/06 05:32 PM (6 years, 3 months ago) |
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Quote:
Krishna said:
was about to post a link about this as well
here's another article
http://www.medpagetoday.com/Neurology/GeneralNeurology/tb2/1934
cool I live in Saskatchewan.
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beavis190
(.Y.)'s
Registered: 01/25/06
Posts: 432
Loc: lost in my head
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: EarthDroid]
#5324892 - 02/21/06 04:24 PM (6 years, 3 months ago) |
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it took that long to find out weed effects your emotions....
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DNKYD
Turtle!
Registered: 09/23/04
Posts: 12,197
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: beavis190]
#5325438 - 02/21/06 06:10 PM (6 years, 3 months ago) |
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Quote:
beavis190 said:
it took that long to find out weed effects your emotions....
WTF are you talking about?
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beavis190
(.Y.)'s
Registered: 01/25/06
Posts: 432
Loc: lost in my head
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: DNKYD]
#5328067 - 02/22/06 12:21 PM (6 years, 3 months ago) |
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Experiments on rats given a potent cannabinoid have shown the drug stimulates the growth of new brain cells. Canadian researchers found that the drug caused neurons to regenerate in the hippocampus, an area that controls mood and emotions, after one month of treatment.
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beavis190
(.Y.)'s
Registered: 01/25/06
Posts: 432
Loc: lost in my head
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: beavis190]
#5328073 - 02/22/06 12:22 PM (6 years, 3 months ago) |
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^^is what im talking about
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DNKYD
Turtle!
Registered: 09/23/04
Posts: 12,197
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Re: High-dose cannabis stimulates growth of brain cells in rats [Re: beavis190]
#5329655 - 02/22/06 08:34 PM (6 years, 3 months ago) |
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It didn't take them "that long to find out weed effects your emotions", it took them that long to find out "that the drug caused neurons to regenerate in the hippocampus." These are two separate things.
Also you have to realize that they are not talking about weed in the article, but a very potent amount of an isolated cannabinoid found in weed. Research hasn't been done as to whether smoked or consumed cannabis has any of the same effects.
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