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nooneman
Stranger
Registered: 04/24/09
Posts: 2,884
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[EU] Genome of Marijuana Sequenced, Published. 2
#14945793 - 08/19/11 03:07 AM (9 months, 3 days ago) |
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http://blogs.nature.com/news/2011/08/weed_sequenced_no_really_weed.html?WT.mc_id=TWT_NatureNews
Weed sequenced. No really - weed. - August 18, 2011
At last, the field of genomics has something to offer Cheech and Chong. DNA sequencing hit a new high last night with the midnight release of the Cannabis sativa genome. The raw sequence was posted on Amazon’s EC2 public cloud computing service by a young company called Medicinal Genomics, which aims to explore the genomes of therapeutic plants.
Thus far the company is only posting the raw sequence reads – meaning that the over 131 billion bases of shotgun sequence have not yet undergone the important and arduous process of being assembled into contiguous chunks. For now, the sequence is fragmented into hundreds of thousands of snippets. But Medicinal Genomics founder Kevin McKernan says he estimates the size of the C. sativa genome to be about 400 million bases – roughly three times the genome of that other weed, the model plant Arabidopsis thaliana.
And in case you're wondering: the DNA was extracted and prepped for sequencing in a laboratory in Amsterdam.
McKernan says he was turned on to the idea of sequencing cannabis by a 2003 publication in Nature Reviews Cancer about the many potential uses – including fighting cancer – of cannabinoids. C. sativa makes about sixty of the compounds. Although THC has gotten the most attention, McKernan hopes his company’s data will help scientists explore a few of the others, and perhaps guide plant breeding programs to generate new Cannabis strains.
No word yet on whether the information can also help researchers construct a van made out of marijuana, but chances are that some enthusiast out there will look into that possibility if the company follows through on its pledge to make genome annotations available as an iPad app next fall.
Also appealing to McKernan: the growing medical marijuana market, which he says is swelling by over 50% a year. “It’s going to have to be a fairly regulated market,” he says, “and regulation is going to come through genetics and fingerprinting of which strains are approved.”
McKernan’s name may ring a bell for sequencing buffs. In 2000, he cofounded Agencourt Biosciences, a spinoff of which eventually created the technology underlying the popular SOLiD sequencing platform now sold by Life Technologies.
McKernan dipped into his own bank account to launch Medicinal Genomics, and says he also has funding from the network of angel investors – mostly friends and family – that helped him get Agencourt off the ground in 2000.
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wowitch17
Growery is Better



Registered: 01/10/06
Posts: 8,537
Loc: Chile
Last seen: 3 months, 12 days
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: nooneman]
#14946916 - 08/19/11 10:15 AM (9 months, 2 days ago) |
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awesome
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That Cenex Guy
The Dark Defender



Registered: 10/22/09
Posts: 360
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: wowitch17]
#14947085 - 08/19/11 10:48 AM (9 months, 2 days ago) |
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Well this is pretty cool news!
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MycoMayhem
Stranger

Registered: 07/27/11
Posts: 807
Last seen: 6 months, 6 days
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: That Cenex Guy]
#14947306 - 08/19/11 11:24 AM (9 months, 2 days ago) |
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OOOO I can't wait for bud with innate resistances to pesticides. NOT
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Tranzfixed
Hunter/Gatherer


Registered: 07/27/11
Posts: 704
Loc: Michigan
Last seen: 16 hours, 18 minutes
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: MycoMayhem]
#14947396 - 08/19/11 11:41 AM (9 months, 2 days ago) |
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Quote:
MycoMayhem said: OOOO I can't wait for bud with innate resistances to pesticides. NOT
don't understand this lol...... but yes cool news indeed! Imagine having a marijuana plant with little thc but with another canabinoid in high percentage. Now that's sativa!
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"The True Guru has bestowed His most pure and sacred teachings. Chanting the name of the Lord, Har, Har, Har, my mind is transfixed and enraptured."
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MycoMayhem
Stranger

Registered: 07/27/11
Posts: 807
Last seen: 6 months, 6 days
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: MycoMayhem]
#14947575 - 08/19/11 12:23 PM (9 months, 2 days ago) |
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Their first priority won't be making fire bud, it will be making the plant hardier, shortening growth time, making it easy to cultivate on a mass scale. Unfortunately when someone like Monsanto comes along this is what happens. Bud quality will be last on the list of shit to do for people with money. This will help big pharma get involved tho, and that is the path to legalization.
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LongStrangeTrip
Deadhead


Registered: 09/19/09
Posts: 3,366
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: MycoMayhem]
#14948606 - 08/19/11 04:31 PM (9 months, 2 days ago) |
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Quote:
MycoMayhem said: Their first priority won't be making fire bud, it will be making the plant hardier, shortening growth time, making it easy to cultivate on a mass scale. Unfortunately when someone like Monsanto comes along this is what happens. Bud quality will be last on the list of shit to do for people with money. This will help big pharma get involved tho, and that is the path to legalization.
Who are "they"? As far as any country is concerned, this stuff is still illegal. I understand people who worry about "big pharma" or someone like Monsanto getting into the cannabis game, and that may seem like some far off inevitability; but we are still talking out of our asses when we vocalize such "worries", I think I get it though
The whole reason Big pharma never got in the cannabis game is because you cannot patent something like a cannabis strain. The article refers to it thus;
"regulation is going to come through genetics and fingerprinting of which strains are approved."
That does not mean that strains will be patented or owned, rather, it refers to cannabis strains that will, somehow or another, be "available" from a pool of "approved" strains. They would have to do this because once the plant is grown, it won't be exactly like the parent plant (unless its a clone). But once your clone your clone your getting more complicated, see what I mean? You can't help genetic variation between plants, once you consider growing conditions and all that jazz. It is just not something you can control like that.
And I remember the riots and protests that sparked from Monsanto's game years back, when trying to overtake the Indian rice market with its patented strain of rice. They did not succeed, I don't think they would with a regulated type of cannabis either.
Whole point; we should be excited about stories like this, not revert to some silly thoughts about how the "man" is going to destroy weed. Fuck that dumb shit. The "man" has got us by the balls right now, how the fuck could it be worse!? People go to jail over cannabis. People kill each other over cannabis markets. We got no where to go but "up" from our current state of affairs. Don't be so worried about the "man" controlling weed; he already does, it needs to be free for fucks sake

-------------------- Nothing I say or do is factual; every single thing I write is a work of fiction. Got no idea what I'm talking about here~
"Once in awhile, you get shown the light, in the strangest of places if you look at it right"~ (Grateful Dead)
"o puer, qui omnia nomini debes"; "You, boy, who owe's everything to a name"~ Mark Anthony
"Nihil est incertius vulgo, nihil obscurius voluntate hominum, nihil fallacius ratione tota comitiorum."; "Nothing is more unpredictable than the mob, nothing more obscure than public opinion, nothing more deceptive than the whole political system."~ Cicero
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plustax
Stranger
Registered: 02/21/10
Posts: 388
Last seen: 27 days, 16 hours
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: LongStrangeTrip]
#14950343 - 08/19/11 10:59 PM (9 months, 2 days ago) |
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Lets get some enzymes in tobacco! (Ultimate cigar would be one that gets you high... a blunt... composed entirely of tobacco)
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tobeacagefighter
Stranger
Registered: 09/01/10
Posts: 33
Last seen: 1 month, 5 days
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: plustax]
#14951258 - 08/20/11 05:33 AM (9 months, 2 days ago) |
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Pot will not be legalized. The problem is our socioeconomic system. Don't be afraid to dream big guys. Check out the Venus Project
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LongStrangeTrip
Deadhead


Registered: 09/19/09
Posts: 3,366
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: tobeacagefighter]
#14951766 - 08/20/11 08:42 AM (9 months, 1 day ago) |
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Quote:
tobeacagefighter said: Pot will not be legalized. The problem is our socioeconomic system. Don't be afraid to dream big guys. Check out the Venus Project
I completely disagree, I think it will be legalized 
And yea the venus project is sweet!!
-------------------- Nothing I say or do is factual; every single thing I write is a work of fiction. Got no idea what I'm talking about here~
"Once in awhile, you get shown the light, in the strangest of places if you look at it right"~ (Grateful Dead)
"o puer, qui omnia nomini debes"; "You, boy, who owe's everything to a name"~ Mark Anthony
"Nihil est incertius vulgo, nihil obscurius voluntate hominum, nihil fallacius ratione tota comitiorum."; "Nothing is more unpredictable than the mob, nothing more obscure than public opinion, nothing more deceptive than the whole political system."~ Cicero
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DoseMuncher
Greenland


Registered: 07/15/09
Posts: 29
Last seen: 5 months, 5 days
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: LongStrangeTrip]
#14952200 - 08/20/11 10:52 AM (9 months, 1 day ago) |
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Thats cool, the article said they sequenced the genome for cannabis sativa I wonder about indica and ruderalis next. possibly even distinguishing the differences between strains so you could tell if this og kush is really og or this blu D is blue dream, thatd bee dopeee
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tobeacagefighter
Stranger
Registered: 09/01/10
Posts: 33
Last seen: 1 month, 5 days
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: LongStrangeTrip]
#14952572 - 08/20/11 12:34 PM (9 months, 1 day ago) |
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Why? It's the top third crime. As in 1/3 of all people arrested are arrested for pot. That supports a whole industry of its own. Not to mention all of the industries that would face complete and utter destruction if it was legalized.
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LongStrangeTrip
Deadhead


Registered: 09/19/09
Posts: 3,366
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: tobeacagefighter]
#14953985 - 08/20/11 06:50 PM (9 months, 1 day ago) |
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Quote:
tobeacagefighter said: Why? It's the top third crime. As in 1/3 of all people arrested are arrested for pot. That supports a whole industry of its own. Not to mention all of the industries that would face complete and utter destruction if it was legalized.
Businesses, industries, politicians; they do not set the rules, they have to go with the times. They can only react to things, like changes in public perception and attitudes. They may fight change, brutally or through the back doors, but they do, sometimes, have to give up.
Perfect example is the civil rights movement (sry if that sounds off topic,but I think the parallel is important none the less). Take a state like Mississippi. They had institutionalized segregation to such a point that all businesses and trades were affected; school children even viewed videos in school about how "nice and acceptable" segregation was. Why it is the right thing to do, and the dangers of what would happen if that were to change. I am sure I don't need to school you on the details of how the various sit ins, bus boycotts, and general peaceful protests turned out for the African Americans (and others, whites included) who actually stood up to, say, the infamous Jacksonville police department. They got their asses kicked and booked.
But that shit changed. Segregation was an, to some, essential part of American life at hat time. It also only lasted for a small number of decades.
We have only had the schedule system since 1972. Think about that for a second. Really, the "drug war" was born then (though I know drug prohibition existed before this time, but this is when our modern American form of "prohibition" was really carved up and set out in stone). That is a measly 40 years. It is wild, let me tell you; young people, from later generations, have so easily come to "accept" the general idea that drugs are something that are...illegal. Its fucking crazy. Do you really, and by you I mean anyone reading this right now, accept that cannabis is illegal? Of course you don't, your probably high right now . It is not crazy to think that this state of affairs will sometime change; it is crazy to think that things could, somehow, never change.

-------------------- Nothing I say or do is factual; every single thing I write is a work of fiction. Got no idea what I'm talking about here~
"Once in awhile, you get shown the light, in the strangest of places if you look at it right"~ (Grateful Dead)
"o puer, qui omnia nomini debes"; "You, boy, who owe's everything to a name"~ Mark Anthony
"Nihil est incertius vulgo, nihil obscurius voluntate hominum, nihil fallacius ratione tota comitiorum."; "Nothing is more unpredictable than the mob, nothing more obscure than public opinion, nothing more deceptive than the whole political system."~ Cicero
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blujay
pass it b*ch!



Registered: 04/01/09
Posts: 4,721
Last seen: 17 days, 8 hours
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Re: [EU] Genome of Marijuana Sequenced, Published. [Re: DoseMuncher]
#14960073 - 08/22/11 07:59 AM (8 months, 30 days ago) |
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http://thevenusproject.com#video
Remember, monorails and skyscrapers solve all our ecological woes.
:/ Buzzkillington
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wat man rly
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